X5J9J1 · X5J9J1_9BACT

Function

function

Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

  • ATP-dependent cleavage of peptide bonds with broad specificity.
    EC:3.4.25.2 (UniProtKB | ENZYME | Rhea)

Activity regulation

Allosterically activated by HslU binding.

Features

Showing features for active site, binding site.

118520406080100120140160180
TypeIDPosition(s)Description
Active site7
Binding site163Na+ (UniProtKB | ChEBI)
Binding site166Na+ (UniProtKB | ChEBI)
Binding site169Na+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular ComponentHslUV protease complex
Cellular Componentproteasome core complex
Molecular Functionmetal ion binding
Molecular Functionthreonine-type endopeptidase activity
Biological Processproteolysis involved in protein catabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    ATP-dependent protease subunit HslV
  • EC number

Gene names

    • Name
      hslV
    • ORF names
      CHV_b0011

Organism names

Accessions

  • Primary accession
    X5J9J1

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.

Protein-protein interaction databases

Family & Domains

Sequence similarities

Belongs to the peptidase T1B family. HslV subfamily.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    185
  • Mass (Da)
    20,311
  • Last updated
    2014-06-11 v1
  • Checksum
    C1692D965BFFF4E5
MIQVKSTTVLAMMHNGAVVIGADGQATFGHTVAKSNVKKVRKLFEGKVLAGFAGSTADAFTLLERFEEKLQSYHGNMKRSAIELAKDWRTDRMLKRLEAMLVVANREGLLMVTGTGDVLEPDYPLAAIGSGSMYAQSAAMALMKHAPHLTAMEMVRESLTITADICIYTNHNFVFESIQDERLTV

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CBQZ010000002
EMBL· GenBank· DDBJ
CDG49864.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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