X5E0F1 · X5E0F1_STAAU

  • Protein
    Bifunctional cystathionine gamma-lyase/homocysteine desulfhydrase
  • Gene
    mccB
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Evidence at protein level
  • Annotation score
    3/5

Function

Cofactor

pyridoxal 5'-phosphate (UniProtKB | Rhea| CHEBI:597326 )

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcytoplasm
Molecular Functioncystathionine gamma-lyase activity
Molecular Functioncystathionine gamma-synthase activity
Molecular Functionidentical protein binding
Molecular FunctionL-cysteine desulfhydrase activity
Molecular FunctionL-cystine L-cysteine-lyase (deaminating)
Molecular Functionpyridoxal phosphate binding
Biological Processtranssulfuration

Keywords

Names & Taxonomy

Protein names

  • Submitted names
    • Bifunctional cystathionine gamma-lyase/homocysteine desulfhydrase
    • Cystathionine beta-lyase
      (EC:4.4.1.1
      , EC:4.4.1.8
      )
    • Cystathionine gamma-synthase
      (EC:2.5.1.48
      )

Gene names

    • Name
      mccB
    • Synonyms
      mccB_2
    • ORF names
      ACR74_13665
      , C0102_13940
      , CNH36_02455
      , EIG96_04490
      , EP54_01605
      , EQ90_13355
      , GO814_02345
      , GO942_04060
      , GQX37_00125
      , HMPREF3211_01439
      , LB359_02510
      , NCTC10702_00840
      , NCTC13131_05913
      , SAMEA1029512_02290
      , SAMEA1029528_01119
      , SAMEA1029536_02405
      , SAMEA2078260_02460
      , SAMEA2078588_01369
      , SAMEA2080344_01429
      , SAMEA2081063_02563
      , SAMEA4008575_01592
      , SAMEA70146418_02721

Organism names

  • Taxonomic identifier
  • Organism
  • Strains
    • CA15
    • M121
    • MRSA_S20
    • PSS7673
    • Newman
  • Taxonomic lineage
    Bacteria > Bacillota > Bacilli > Bacillales > Staphylococcaceae > Staphylococcus

Accessions

  • Primary accession
    X5E0F1
  • Secondary accessions
    • A0A1E8WZL2

Proteomes

Subcellular Location

PTM/Processing

Features

Showing features for modified residue.

TypeIDPosition(s)Description
Modified residue196N6-(pyridoxal phosphate)lysine

Family & Domains

Sequence similarities

Belongs to the trans-sulfuration enzymes family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    380
  • Mass (Da)
    41,279
  • Last updated
    2014-06-11 v1
  • Checksum
    21540C56812D5959
MNKKTKLIHGGHTTDDYTGAVTTPIYQTSTYLQDDIGDLRQGYEYSRTANPTRSSVESVIATLENGKHGFAFSSGVAAISAVVMLLDKGDHIILNSDVYGGTYRALTKVFTRFGIEVDFVDTTHTDSIVQAIRPTTKMLFIETPSNPLLRVTDIKKSAEIAKEHGLISVVDNTFMTPYYQNPLDLGIDIVLHSATKYLGGHSDVVAGLVATSDDKLAERLAFISNSTGGILGPQDSYLLVRGIKTLGLRMEQINRSVIEIIKMLQAHPAVQQVFHPSIESHLNHDVHMAQADGHTGVIAFEVKNTESAKQLIKATSYYTLAESLGAVESLISVPALMTHASIPADIRAKEGITDGLVRISVGIEDTEDLVDDLKQALDTL

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP023391
EMBL· GenBank· DDBJ
ATC70555.1
EMBL· GenBank· DDBJ
Genomic DNA
CACTPI010000004
EMBL· GenBank· DDBJ
CAA4106924.1
EMBL· GenBank· DDBJ
Genomic DNA
CACTOE010000018
EMBL· GenBank· DDBJ
CAA4151426.1
EMBL· GenBank· DDBJ
Genomic DNA
CACTPG010000021
EMBL· GenBank· DDBJ
CAA4177515.1
EMBL· GenBank· DDBJ
Genomic DNA
CACTQT010000018
EMBL· GenBank· DDBJ
CAA4395249.1
EMBL· GenBank· DDBJ
Genomic DNA
CACTWD010000021
EMBL· GenBank· DDBJ
CAA4704441.1
EMBL· GenBank· DDBJ
Genomic DNA
CACUNS010000006
EMBL· GenBank· DDBJ
CAA6079352.1
EMBL· GenBank· DDBJ
Genomic DNA
CACURZ010000006
EMBL· GenBank· DDBJ
CAA6349903.1
EMBL· GenBank· DDBJ
Genomic DNA
CAIGXB010000005
EMBL· GenBank· DDBJ
CAC5794270.1
EMBL· GenBank· DDBJ
Genomic DNA
CAIIGD010000015
EMBL· GenBank· DDBJ
CAC8236638.1
EMBL· GenBank· DDBJ
Genomic DNA
UAUZ02000004
EMBL· GenBank· DDBJ
CAD7354938.1
EMBL· GenBank· DDBJ
Genomic DNA
LALJ01000044
EMBL· GenBank· DDBJ
KMR35338.1
EMBL· GenBank· DDBJ
Genomic DNA
LALQ01000004
EMBL· GenBank· DDBJ
KMR58344.1
EMBL· GenBank· DDBJ
Genomic DNA
LFVK01000013
EMBL· GenBank· DDBJ
KSA73330.1
EMBL· GenBank· DDBJ
Genomic DNA
LRQH01000112
EMBL· GenBank· DDBJ
KXA35996.1
EMBL· GenBank· DDBJ
Genomic DNA
JAIUEN010000012
EMBL· GenBank· DDBJ
MCE3361233.1
EMBL· GenBank· DDBJ
Genomic DNA
WPTS01000017
EMBL· GenBank· DDBJ
MVK33974.1
EMBL· GenBank· DDBJ
Genomic DNA
WPXC01000008
EMBL· GenBank· DDBJ
MVM09860.1
EMBL· GenBank· DDBJ
Genomic DNA
JAANEC010000001
EMBL· GenBank· DDBJ
NUY10973.1
EMBL· GenBank· DDBJ
Genomic DNA
PKSU01000015
EMBL· GenBank· DDBJ
PZL78395.1
EMBL· GenBank· DDBJ
Genomic DNA
RQSX01000089
EMBL· GenBank· DDBJ
RZH94894.1
EMBL· GenBank· DDBJ
Genomic DNA
UHBY01000003
EMBL· GenBank· DDBJ
SUL32491.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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