X2L5V2 · X2L5V2_9TELE
- ProteinCytochrome b
- GeneCYTB
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids379 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
Cofactor
Protein has several cofactor binding sites:
Note: Binds 2 heme groups non-covalently.
Note: Binds 2 heme groups non-covalently.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 83 | Fe (UniProtKB | ChEBI) of heme b b562 (UniProtKB | ChEBI); axial binding residue | ||||
Sequence: H | ||||||
Binding site | 97 | Fe (UniProtKB | ChEBI) of heme b b566 (UniProtKB | ChEBI); axial binding residue | ||||
Sequence: H | ||||||
Binding site | 182 | Fe (UniProtKB | ChEBI) of heme b b562 (UniProtKB | ChEBI); axial binding residue | ||||
Sequence: H | ||||||
Binding site | 196 | Fe (UniProtKB | ChEBI) of heme b b566 (UniProtKB | ChEBI); axial binding residue | ||||
Sequence: H | ||||||
Binding site | 201 | a ubiquinone (UniProtKB | ChEBI) | ||||
Sequence: H |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | mitochondrial inner membrane | |
Cellular Component | respiratory chain complex III | |
Molecular Function | metal ion binding | |
Molecular Function | ubiquinol-cytochrome-c reductase activity | |
Biological Process | respiratory electron transport chain |
Keywords
- Biological process
- Ligand
Names & Taxonomy
Protein names
- Recommended nameCytochrome b
Gene names
Encoded on
- Mitochondrion
Organism names
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Neoteleostei > Acanthomorphata > Anabantaria > Synbranchiformes > Mastacembelidae > Mastacembelus
Accessions
- Primary accessionX2L5V2
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Membrane ; Multi-pass membrane protein
Mitochondrion inner membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 30-56 | Helical | ||||
Sequence: WWNFGSLLGLCLMTQILTGLFLAMHYT | ||||||
Transmembrane | 77-98 | Helical | ||||
Sequence: WLIRNIHANGASLFFICIYLHI | ||||||
Transmembrane | 113-133 | Helical | ||||
Sequence: WNIGVILLLLTMMTAFVGYVL | ||||||
Transmembrane | 145-166 | Helical | ||||
Sequence: VITNLLSAVPYIGNTLVQWIWG | ||||||
Transmembrane | 178-200 | Helical | ||||
Sequence: FFAFHFLFPFIIAAATMVHLLFL | ||||||
Transmembrane | 229-250 | Helical | ||||
Sequence: LMGFILALITLTSLALFSPNLL | ||||||
Transmembrane | 288-308 | Helical | ||||
Sequence: LGGVLALLASILVLMLVPVLH | ||||||
Transmembrane | 320-341 | Helical | ||||
Sequence: VSQLLFWTLITDVIILTWIGGM | ||||||
Transmembrane | 347-372 | Helical | ||||
Sequence: FIIIGQIASLLYFLLFLLLIPATGWA |
Keywords
- Cellular component
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 1-209 | Cytochrome b/b6 N-terminal region profile | ||||
Sequence: MANLRKTHPLLKIANNALIDLPAPSNISAWWNFGSLLGLCLMTQILTGLFLAMHYTSDISMAFSSVVHICRDVNYGWLIRNIHANGASLFFICIYLHIGRGLYYGSYLYKETWNIGVILLLLTMMTAFVGYVLPWGQMSFWGATVITNLLSAVPYIGNTLVQWIWGGFSVDNATLTRFFAFHFLFPFIIAAATMVHLLFLHETGSNNPT | ||||||
Domain | 210-379 | Cytochrome b/b6 C-terminal region profile | ||||
Sequence: GLNSDVDKIPFHPYYSYKDLMGFILALITLTSLALFSPNLLGDPDNFTPANPLVTPPHIKPEWYFLFAYAILRSIPNKLGGVLALLASILVLMLVPVLHTSKQRSLTFRPVSQLLFWTLITDVIILTWIGGMPVEHPFIIIGQIASLLYFLLFLLLIPATGWAENKILKK |
Sequence similarities
Belongs to the cytochrome b family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length379
- Mass (Da)42,516
- Last updated2014-06-11 v1
- Checksum5FD532FCA66DF1A1
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
KJ184553 EMBL· GenBank· DDBJ | AHN95397.1 EMBL· GenBank· DDBJ | Genomic DNA |