X2JG79 · X2JG79_DROME
- ProteinSupervillin, isoform W
- GeneSvil
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids3040 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score3/5
Function
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | actin cytoskeleton | |
Cellular Component | cytoplasm | |
Molecular Function | actin filament binding | |
Molecular Function | phosphatidylinositol-4,5-bisphosphate binding | |
Biological Process | actin filament severing | |
Biological Process | actin polymerization or depolymerization | |
Biological Process | barbed-end actin filament capping |
Keywords
- Molecular function
Names & Taxonomy
Protein names
- Submitted names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Metazoa > Ecdysozoa > Arthropoda > Hexapoda > Insecta > Pterygota > Neoptera > Endopterygota > Diptera > Brachycera > Muscomorpha > Ephydroidea > Drosophilidae > Drosophila > Sophophora
Accessions
- Primary accessionX2JG79
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Expression
Gene expression databases
Structure
Family & Domains
Features
Showing features for region, compositional bias, domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 18-105 | Disordered | ||||
Sequence: SPEKYRPYHLNGSKSSGAMDFPRYRKTIAASSDLSTAPATAKTSCQPPEPLKQKPPQQQTTKDSEDSSSQKSAPVQSYRGQHPHFHHH | ||||||
Compositional bias | 46-64 | Polar residues | ||||
Sequence: AASSDLSTAPATAKTSCQP | ||||||
Compositional bias | 72-94 | Polar residues | ||||
Sequence: PPQQQTTKDSEDSSSQKSAPVQS | ||||||
Compositional bias | 139-161 | Polar residues | ||||
Sequence: TPSTQLVEQRSFPKSSTATKDPP | ||||||
Region | 139-286 | Disordered | ||||
Sequence: TPSTQLVEQRSFPKSSTATKDPPLPISNPARGTFFRGDSASSDSHSRLRRSQQRTGSEGRFFRYSQGSVSPTKGEPPIGHEGGEQPPVVASHSPITSTSTTTISSCNPVEQASPPPTNVVNPSGSGRNSRHKQRFHSRSRRAVRVRSE | ||||||
Compositional bias | 180-194 | Basic and acidic residues | ||||
Sequence: SDSHSRLRRSQQRTG | ||||||
Compositional bias | 195-210 | Polar residues | ||||
Sequence: SEGRFFRYSQGSVSPT | ||||||
Compositional bias | 228-266 | Polar residues | ||||
Sequence: ASHSPITSTSTTTISSCNPVEQASPPPTNVVNPSGSGRN | ||||||
Region | 303-328 | Disordered | ||||
Sequence: LENSSSSSSSSNEQEKKKDQEQPKTT | ||||||
Region | 340-371 | Disordered | ||||
Sequence: HHYLNPPMSSGNSGGSSGNPKQQQQQQQQQQL | ||||||
Compositional bias | 345-371 | Polar residues | ||||
Sequence: PPMSSGNSGGSSGNPKQQQQQQQQQQL | ||||||
Compositional bias | 388-421 | Polar residues | ||||
Sequence: LPAVSSSSDEEGSLRTLHSSRKVTNLNAKSTSLP | ||||||
Region | 388-434 | Disordered | ||||
Sequence: LPAVSSSSDEEGSLRTLHSSRKVTNLNAKSTSLPPEEGLSGDVSLES | ||||||
Region | 534-772 | Disordered | ||||
Sequence: ANGHDQSDPEDDHQTDHHQHAHQSLPVEPKSHHHQHHQATNARRFITRTTRSASRQSSAGHSPPPPLHRSDDSSSSSPSPTRRRNKPGGAPAATDPPSSSANGNSSAYETAATTVMTHDQQRDPPVEVPKALNVEPPQPEDIVLGSCPTASAHSDKKKEEEQRNRYSSPVSPKASSNGGVQAQRRLSNSELSPKSPGASGFTSEPVASATANRVPTRSASHPVDTPPTQRRQPLVAVSS | ||||||
Compositional bias | 538-568 | Basic and acidic residues | ||||
Sequence: DQSDPEDDHQTDHHQHAHQSLPVEPKSHHHQ | ||||||
Compositional bias | 575-616 | Polar residues | ||||
Sequence: ARRFITRTTRSASRQSSAGHSPPPPLHRSDDSSSSSPSPTRR | ||||||
Compositional bias | 628-653 | Polar residues | ||||
Sequence: DPPSSSANGNSSAYETAATTVMTHDQ | ||||||
Compositional bias | 685-699 | Basic and acidic residues | ||||
Sequence: AHSDKKKEEEQRNRY | ||||||
Compositional bias | 700-772 | Polar residues | ||||
Sequence: SSPVSPKASSNGGVQAQRRLSNSELSPKSPGASGFTSEPVASATANRVPTRSASHPVDTPPTQRRQPLVAVSS | ||||||
Region | 802-898 | Disordered | ||||
Sequence: RMRPRSSTMSTENTENGRRDHLANLQLSPVQKQKRTPEVSPRRFGDRDKSAKRKSNLNRSLTEEATKDGDEVASSTRRRRRRELGMARPLVPGDDDA | ||||||
Compositional bias | 837-898 | Basic and acidic residues | ||||
Sequence: TPEVSPRRFGDRDKSAKRKSNLNRSLTEEATKDGDEVASSTRRRRRRELGMARPLVPGDDDA | ||||||
Region | 1000-1021 | Disordered | ||||
Sequence: KSTDEGGSALGATNQNSPPAPN | ||||||
Compositional bias | 1006-1021 | Polar residues | ||||
Sequence: GSALGATNQNSPPAPN | ||||||
Region | 1106-1159 | Disordered | ||||
Sequence: EAGTGLSPAQAHGILKQSSYDSSKSDGCPSATESQPHSILKKKDSLSTPSDGGC | ||||||
Compositional bias | 1116-1150 | Polar residues | ||||
Sequence: AHGILKQSSYDSSKSDGCPSATESQPHSILKKKDS | ||||||
Region | 1194-1295 | Disordered | ||||
Sequence: PILKQESTSSEEAVRPPKPILKKKSFGEADEHEIRPILKSSRKSSREEFDLSGLENEVNDSLSSILKTDSPSKRRSLGSALHDLEESTTSPSMLKRRTRSLE | ||||||
Compositional bias | 1209-1246 | Basic and acidic residues | ||||
Sequence: PPKPILKKKSFGEADEHEIRPILKSSRKSSREEFDLSG | ||||||
Compositional bias | 1249-1268 | Polar residues | ||||
Sequence: NEVNDSLSSILKTDSPSKRR | ||||||
Region | 1348-1376 | Disordered | ||||
Sequence: TSRAAGGANSSWESPLQASSAEHGAPTTP | ||||||
Compositional bias | 1349-1371 | Polar residues | ||||
Sequence: SRAAGGANSSWESPLQASSAEHG | ||||||
Region | 1535-1569 | Disordered | ||||
Sequence: AIQSLSDETAASASANSTSTTTATTMTPPSGLTRS | ||||||
Compositional bias | 1583-1626 | Polar residues | ||||
Sequence: QEQSRNQRATGTTNSRQSPPASSAEVSSSAADNSMHSDERSTPN | ||||||
Region | 1583-1642 | Disordered | ||||
Sequence: QEQSRNQRATGTTNSRQSPPASSAEVSSSAADNSMHSDERSTPNATIDAEFGKPSTEPLK | ||||||
Region | 1676-1697 | Disordered | ||||
Sequence: HATVSNLRKSATSADATRAASD | ||||||
Region | 1737-1813 | Disordered | ||||
Sequence: QPRSLARDDAAGNCASASEGESSGGREIEAIIKNSAVARRRRQQQQQSQQQNQPDGNLVAKSKSHSGISAPIGLGPQ | ||||||
Compositional bias | 1774-1800 | Polar residues | ||||
Sequence: ARRRRQQQQQSQQQNQPDGNLVAKSKS | ||||||
Region | 1830-1870 | Disordered | ||||
Sequence: AKEEDTSSSSNTSSAKESPDKKDLRQEQAEASGDSSHPTAL | ||||||
Compositional bias | 1845-1859 | Basic and acidic residues | ||||
Sequence: KESPDKKDLRQEQAE | ||||||
Region | 2028-2115 | Disordered | ||||
Sequence: NQPQLGLAKSPSMMVTSSTSTNSTSKSALRSLSVNPEEEGPTSLSRSNSSSSESDGERKSPQNAKQNKELANNKSAAAPTNVGARIQV | ||||||
Compositional bias | 2030-2084 | Polar residues | ||||
Sequence: PQLGLAKSPSMMVTSSTSTNSTSKSALRSLSVNPEEEGPTSLSRSNSSSSESDGE | ||||||
Compositional bias | 2092-2107 | Polar residues | ||||
Sequence: KQNKELANNKSAAAPT | ||||||
Domain | 2977-3040 | HP | ||||
Sequence: QMTQTEYPLEVLKARPLPEGVEPTRLEVYLNAEDFQAALGCSRAEFEQLPIWKQTKLKKERGLF |
Sequence similarities
Belongs to the villin/gelsolin family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length3,040
- Mass (Da)334,451
- Last updated2014-06-11 v1
- Checksum75217549152430DF
Computationally mapped potential isoform sequences
There are 24 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
X2JAM4 | X2JAM4_DROME | Svil | 4526 | ||
Q9W013 | Q9W013_DROME | Svil | 475 | ||
Q9W016 | Q9W016_DROME | Svil | 2223 | ||
Q9W018 | Q9W018_DROME | Svil | 1933 | ||
M9PEC5 | M9PEC5_DROME | Svil | 1111 | ||
M9PDU5 | M9PDU5_DROME | Svil | 1519 | ||
X2J8M7 | X2J8M7_DROME | Svil | 3473 | ||
Q8IRF0 | Q8IRF0_DROME | Svil | 416 | ||
E1JIB9 | E1JIB9_DROME | Svil | 1702 | ||
E1JIC0 | E1JIC0_DROME | Svil | 1400 | ||
M9NEY0 | M9NEY0_DROME | Svil | 407 | ||
M9MRU6 | M9MRU6_DROME | Svil | 663 | ||
M9MRZ4 | M9MRZ4_DROME | Svil | 2028 | ||
M9MRN1 | M9MRN1_DROME | Svil | 1872 | ||
M9MRN5 | M9MRN5_DROME | Svil | 1967 | ||
M9MRQ1 | M9MRQ1_DROME | Svil | 266 | ||
M9MRP8 | M9MRP8_DROME | Svil | 1446 | ||
Q0E8J1 | Q0E8J1_DROME | Svil | 1156 | ||
X2JC02 | X2JC02_DROME | Svil | 3359 | ||
X2JCG0 | X2JCG0_DROME | Svil | 3115 | ||
M9NFH6 | M9NFH6_DROME | Svil | 1621 | ||
Q7KV92 | Q7KV92_DROME | Svil | 1514 | ||
Q7KV98 | Q7KV98_DROME | Svil | 1877 | ||
X2JAL9 | X2JAL9_DROME | Svil | 1574 |
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 46-64 | Polar residues | ||||
Sequence: AASSDLSTAPATAKTSCQP | ||||||
Compositional bias | 72-94 | Polar residues | ||||
Sequence: PPQQQTTKDSEDSSSQKSAPVQS | ||||||
Compositional bias | 139-161 | Polar residues | ||||
Sequence: TPSTQLVEQRSFPKSSTATKDPP | ||||||
Compositional bias | 180-194 | Basic and acidic residues | ||||
Sequence: SDSHSRLRRSQQRTG | ||||||
Compositional bias | 195-210 | Polar residues | ||||
Sequence: SEGRFFRYSQGSVSPT | ||||||
Compositional bias | 228-266 | Polar residues | ||||
Sequence: ASHSPITSTSTTTISSCNPVEQASPPPTNVVNPSGSGRN | ||||||
Compositional bias | 345-371 | Polar residues | ||||
Sequence: PPMSSGNSGGSSGNPKQQQQQQQQQQL | ||||||
Compositional bias | 388-421 | Polar residues | ||||
Sequence: LPAVSSSSDEEGSLRTLHSSRKVTNLNAKSTSLP | ||||||
Compositional bias | 538-568 | Basic and acidic residues | ||||
Sequence: DQSDPEDDHQTDHHQHAHQSLPVEPKSHHHQ | ||||||
Compositional bias | 575-616 | Polar residues | ||||
Sequence: ARRFITRTTRSASRQSSAGHSPPPPLHRSDDSSSSSPSPTRR | ||||||
Compositional bias | 628-653 | Polar residues | ||||
Sequence: DPPSSSANGNSSAYETAATTVMTHDQ | ||||||
Compositional bias | 685-699 | Basic and acidic residues | ||||
Sequence: AHSDKKKEEEQRNRY | ||||||
Compositional bias | 700-772 | Polar residues | ||||
Sequence: SSPVSPKASSNGGVQAQRRLSNSELSPKSPGASGFTSEPVASATANRVPTRSASHPVDTPPTQRRQPLVAVSS | ||||||
Compositional bias | 837-898 | Basic and acidic residues | ||||
Sequence: TPEVSPRRFGDRDKSAKRKSNLNRSLTEEATKDGDEVASSTRRRRRRELGMARPLVPGDDDA | ||||||
Compositional bias | 1006-1021 | Polar residues | ||||
Sequence: GSALGATNQNSPPAPN | ||||||
Compositional bias | 1116-1150 | Polar residues | ||||
Sequence: AHGILKQSSYDSSKSDGCPSATESQPHSILKKKDS | ||||||
Compositional bias | 1209-1246 | Basic and acidic residues | ||||
Sequence: PPKPILKKKSFGEADEHEIRPILKSSRKSSREEFDLSG | ||||||
Compositional bias | 1249-1268 | Polar residues | ||||
Sequence: NEVNDSLSSILKTDSPSKRR | ||||||
Compositional bias | 1349-1371 | Polar residues | ||||
Sequence: SRAAGGANSSWESPLQASSAEHG | ||||||
Compositional bias | 1583-1626 | Polar residues | ||||
Sequence: QEQSRNQRATGTTNSRQSPPASSAEVSSSAADNSMHSDERSTPN | ||||||
Compositional bias | 1774-1800 | Polar residues | ||||
Sequence: ARRRRQQQQQSQQQNQPDGNLVAKSKS | ||||||
Compositional bias | 1845-1859 | Basic and acidic residues | ||||
Sequence: KESPDKKDLRQEQAE | ||||||
Compositional bias | 2030-2084 | Polar residues | ||||
Sequence: PQLGLAKSPSMMVTSSTSTNSTSKSALRSLSVNPEEEGPTSLSRSNSSSSESDGE | ||||||
Compositional bias | 2092-2107 | Polar residues | ||||
Sequence: KQNKELANNKSAAAPT |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AE014296 EMBL· GenBank· DDBJ | AHN57940.1 EMBL· GenBank· DDBJ | Genomic DNA |