X2C1X5 · X2C1X5_LEPPY
- ProteinMitogen-activated protein kinase
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids443 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
Catalytic activity
- ATP + L-seryl-[protein] = ADP + H+ + O-phospho-L-seryl-[protein]
Cofactor
Activity regulation
Activated by threonine and tyrosine phosphorylation.
Features
Showing features for binding site.
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | ATP binding | |
Molecular Function | MAP kinase activity |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameMitogen-activated protein kinase
- EC number
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Discoba > Euglenozoa > Kinetoplastea > Metakinetoplastina > Trypanosomatida > Trypanosomatidae > Leishmaniinae > Leptomonas
Accessions
- Primary accessionX2C1X5
Proteomes
Organism-specific databases
Structure
Family & Domains
Features
Showing features for domain, region, compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 13-302 | Protein kinase | ||||
Sequence: YEIQTQLGQGAYGIVWRAVERKHNRIVALKKIYDAFQNSTDAQRTFREIMFLHRLHHPNIIKLLHVHRAYNDRDIYLVFEYMETDLHVVIRANILEDIHKQFIIYQLLKTMKYLHSAEILHRDMKPSNLLVNSDCTMKVADFGLARSILSLESEQASRPVLTDYIATRWYRPPEVLLGSTRYTKGVDMWSVGCILGELMLGKPIFPGRSTTNQLEIIISVTGRPSAADIAATNSQFAQAMLRDISSSHPRTFAELLPNASADALDLIQRLMCFNPNRRITAAEALEHPYV | ||||||
Region | 355-443 | Disordered | ||||
Sequence: PVATGTTATHGTGPSSGGATRPTGSSLASRSTANSNAAASRLAANRVKATSTGATAEPTATKAHVRQVPRSDVSGTGSRLGTRDVAARK | ||||||
Compositional bias | 356-412 | Polar residues | ||||
Sequence: VATGTTATHGTGPSSGGATRPTGSSLASRSTANSNAAASRLAANRVKATSTGATAEP |
Sequence similarities
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusFragment
- Length443
- Mass (Da)49,326
- Last updated2014-06-11 v1
- ChecksumB93E2BB7DE8E9D86
Features
Showing features for compositional bias, non-terminal residue.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 356-412 | Polar residues | ||||
Sequence: VATGTTATHGTGPSSGGATRPTGSSLASRSTANSNAAASRLAANRVKATSTGATAEP | ||||||
Non-terminal residue | 443 | |||||
Sequence: K |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
KC543604 EMBL· GenBank· DDBJ | AGG11616.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
LGTL01000009 EMBL· GenBank· DDBJ | KPA79930.1 EMBL· GenBank· DDBJ | Genomic DNA |