W8Y6I8 · W8Y6I8_BACTU

Function

function

Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

Catalytic activity

Cofactor

[4Fe-4S] cluster (UniProtKB | Rhea| CHEBI:49883 )

Pathway

Carbohydrate metabolism; tricarboxylic acid cycle; isocitrate from oxaloacetate: step 2/2.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Molecular Function4 iron, 4 sulfur cluster binding
Molecular Functionaconitate hydratase activity
Molecular Functionmetal ion binding
Biological Processtricarboxylic acid cycle

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Aconitate hydratase
  • EC number
  • Short names
    Aconitase

Gene names

    • ORF names
      BTDB27_003451

Organism names

  • Taxonomic identifier
  • Strain
    • DB27
  • Taxonomic lineage
    Bacteria > Bacillota > Bacilli > Bacillales > Bacillaceae > Bacillus > Bacillus cereus group

Accessions

  • Primary accession
    W8Y6I8

Proteomes

Interaction

Subunit

Monomer.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain76-571Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Domain701-828Aconitase A/isopropylmalate dehydratase small subunit swivel

Sequence similarities

Belongs to the aconitase/IPM isomerase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    907
  • Mass (Da)
    98,955
  • Last updated
    2014-05-14 v1
  • Checksum
    15F13166042A614D
MVKHNPFQSRATFEVDGKTYHYYDLKALENAGVGNVSQLPYSVKVLLESVLRQVDGRVITEEHVTNLAKWGTKDVQDIDVPFKPSRVILQDFTGVPAVVDLASLRKAMADMGGDPDKINPEITVDLVIDHSVQVDRAGTADALAFNMDLEFKRNEERYKFLSWAQKSFDNYRAVPPATGIVHQVNLEYLAPVVHAVKNAEGDLVAYPDSLVGTDSHTTMINGIGVLGWGVGGIEAEAGMLGQPSYFPVPEVIGVKLTGTLPSGTTATDVALKVTQVLRQKGVVGKFVEFFGNGLKSMPLADRATISNMAPEYGATCGFFPIDDISLEYLRLTGRDEEQIRVVEEYCKANGLFYTADSKDPIYTDLVEIDLNTIESNLSGPKRPQDLIPLSDMKDAFHEAVVAPVGTQGLGFNEQEFDKEVKVTLEDKEVTMKTGAIAIAAITSCTNTSNPYVLIGAGLVAKKAIEKGLVVPEYVKTSLAPGSKVVTEYLDKSGLTTYLDQLGFQTVGYGCTTCIGNSGPLAPELEEAIAANDLLVTSVLSGNRNFEGRIHPLVKANYLASPPLVVAYALAGTVDIDLKNDEIGKDANGNAVYFNDIWPSAKEIEDVVQSVVTSELFKKEYAQVFNSNERWNEIQTSNEALYTWDNDSTYIQNPPFFEGLSKEPGEVETLSGLRVVGKFGDSVTTDHISPAGSIGKHTPAGRYLLENGVQPVDFNSYGSRRGNHEVMMRGTFANIRIKNQIAPGTEGGYTTYWPTGEVTSIYDAAMKYKEDGTGLLVVAGKDYGMGSSRDWAAKGTNLLGIKAVIAESFERIHRSNLVLMGVLPLQFKDGESAETLGLVGNESFEIQIDKTVRPRDLVKVVATDADGNEKQFEVVARFDSEVEIDYYRHGGILQMVLREKIEESKVSN

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
HG810018
EMBL· GenBank· DDBJ
CDN37109.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

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