W8CMH4 · W8CMH4_CHICK
- ProteinGLI-Kruppel family member GLI3
- GeneGLI3
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids323 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score2/5
Function
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Cellular Component | nucleus | |
Molecular Function | DNA-binding transcription factor activity, RNA polymerase II-specific | |
Molecular Function | metal ion binding | |
Molecular Function | RNA polymerase II cis-regulatory region sequence-specific DNA binding | |
Biological Process | smoothened signaling pathway |
Keywords
- Molecular function
- Ligand
Names & Taxonomy
Protein names
- Submitted names
Gene names
Organism names
- Organism
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Archelosauria > Archosauria > Dinosauria > Saurischia > Theropoda > Coelurosauria > Aves > Neognathae > Galloanserae > Galliformes > Phasianidae > Phasianinae > Gallus
Accessions
- Primary accessionW8CMH4
Organism-specific databases
PTM/Processing
Keywords
- PTM
Structure
Family & Domains
Features
Showing features for domain, compositional bias, region.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 7-36 | C2H2-type | ||||
Sequence: HKCTFEGCTKAYSRLENLKTHLRSHTGEKP | ||||||
Domain | 37-67 | C2H2-type | ||||
Sequence: YVCEHEGCNKAFSNASDRAKHQNRTHSNEKP | ||||||
Domain | 68-98 | C2H2-type | ||||
Sequence: YVCKIPGCTKRYTDPSSLRKHVKTVHGPEAH | ||||||
Compositional bias | 81-113 | Basic and acidic residues | ||||
Sequence: DPSSLRKHVKTVHGPEAHVTKKQRGDIHPRPPP | ||||||
Region | 81-193 | Disordered | ||||
Sequence: DPSSLRKHVKTVHGPEAHVTKKQRGDIHPRPPPPRDPGSHSQTRSPGQQTQGATGEQKDLNSTTSRREECLQVKAVKSEKPMTSQPSPGGQSTCSSEQSPISNYSNNGIELTL | ||||||
Compositional bias | 120-140 | Polar residues | ||||
Sequence: HSQTRSPGQQTQGATGEQKDL | ||||||
Compositional bias | 141-155 | Basic and acidic residues | ||||
Sequence: NSTTSRREECLQVKA | ||||||
Compositional bias | 158-193 | Polar residues | ||||
Sequence: SEKPMTSQPSPGGQSTCSSEQSPISNYSNNGIELTL | ||||||
Region | 251-291 | Disordered | ||||
Sequence: LPRLNPVPPSKAPTLPPXIGNGTQSNSSCSVGGSMTIXPNR | ||||||
Compositional bias | 267-291 | Polar residues | ||||
Sequence: PXIGNGTQSNSSCSVGGSMTIXPNR |
Sequence similarities
Belongs to the GLI C2H2-type zinc-finger protein family.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusFragment
- Length323
- Mass (Da)35,134
- Last updated2014-05-14 v1
- Checksum5D517096B11486CB
Features
Showing features for non-terminal residue, compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Non-terminal residue | 1 | |||||
Sequence: H | ||||||
Compositional bias | 81-113 | Basic and acidic residues | ||||
Sequence: DPSSLRKHVKTVHGPEAHVTKKQRGDIHPRPPP | ||||||
Compositional bias | 120-140 | Polar residues | ||||
Sequence: HSQTRSPGQQTQGATGEQKDL | ||||||
Compositional bias | 141-155 | Basic and acidic residues | ||||
Sequence: NSTTSRREECLQVKA | ||||||
Compositional bias | 158-193 | Polar residues | ||||
Sequence: SEKPMTSQPSPGGQSTCSSEQSPISNYSNNGIELTL | ||||||
Compositional bias | 267-291 | Polar residues | ||||
Sequence: PXIGNGTQSNSSCSVGGSMTIXPNR | ||||||
Non-terminal residue | 323 | |||||
Sequence: R |