W7WCB7 · W7WCB7_9BURK

  • Protein
    Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE
  • Gene
    ubiE_2
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    4/5

Function

function

Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Pathway

Cofactor biosynthesis; ubiquinone biosynthesis.
Quinol/quinone metabolism; menaquinone biosynthesis; menaquinol from 1,4-dihydroxy-2-naphthoate: step 2/2.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site211S-adenosyl-L-methionine (UniProtKB | ChEBI)
Binding site232S-adenosyl-L-methionine (UniProtKB | ChEBI)
Binding site258-259S-adenosyl-L-methionine (UniProtKB | ChEBI)

GO annotations

AspectTerm
Molecular Function2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity
Molecular Functiondemethylmenaquinone methyltransferase activity
Molecular Functionmetal ion binding
Molecular FunctionS-adenosylmethionine:2-demethylmenaquinol methyltransferase activity
Molecular FunctionS-adenosylmethionine:2-demethylmenaquinol-7 methyltransferase activity
Molecular FunctionS-adenosylmethionine:2-demethylquinol-8 methyltransferase activity
Biological Processaerobic respiration
Biological Processmenaquinone biosynthetic process
Biological Processmethylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE
  • EC number
  • Alternative names
    • 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase
    • Demethylmenaquinone methyltransferase

Gene names

    • Name
      ubiE_2
    • Synonyms
      ubiE
    • ORF names
      Y694_01905

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • T29-B
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Betaproteobacteria > Burkholderiales > Sphaerotilaceae > Methylibium

Accessions

  • Primary accession
    W7WCB7

Proteomes

Family & Domains

Features

Showing features for domain, region.

TypeIDPosition(s)Description
Domain15-89Gamma-butyrobetaine hydroxylase-like N-terminal
Region100-125Disordered

Sequence similarities

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    440
  • Mass (Da)
    47,827
  • Last updated
    2014-04-16 v1
  • Checksum
    AD2EEB1A3CB4429D
MAGLTPDTPTPTALTVHQQSRVLEIAFSDGAQFRLPFELLRVYSPSAEVQGHGPGQEVLQTGKRNVDIVELEPVGNYAVQPTFSDGHNSVCSLGTTSTTWVASRSSSGRPTKRGSPPPGWTATPPWSKLAVRPAATTTEDCGMGSTHFGFQNVDEKEKAGRVRGVFDAVASKYDVMNDLMSLGLHRAWKAYTVAVANVRDGDRVLDIAGGTGDLARAFSRRVGSRGMVVHTDINEAMLRTGRDRLLDEGLVLPTAICDAEHLPFASGSFDVVSVAFGLRNMTHKEQALAEMARVLKPGGRLLVLEFSKVAKPLEKAYDWYSFQVLPRLGKWVANDADSYRYLAESIRMHPDQAALKGLMRAAGFGHVDVHNMAGGVVALHAGFVVDATNRRDRRFPVSIVRISQRPCRLSGGPRYWVESPPRPTGTLDWSFSTGAPAFVE

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AZSN01000039
EMBL· GenBank· DDBJ
EWS60306.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
FeedbackHelp