W7W7R7 · W7W7R7_9BURK
- ProteinBifunctional adenosylcobalamin biosynthesis protein
- GenecobP_3
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids197 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.
Catalytic activity
- adenosylcob(III)inamide + ATP = adenosylcob(III)inamide phosphate + ADP + H+
Pathway
Cofactor biosynthesis; adenosylcobalamin biosynthesis; adenosylcobalamin from cob(II)yrinate a,c-diamide: step 5/7.
Cofactor biosynthesis; adenosylcobalamin biosynthesis; adenosylcobalamin from cob(II)yrinate a,c-diamide: step 6/7.
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 19-26 | GTP (UniProtKB | ChEBI) | ||||
Sequence: GGQRSGKS | ||||||
Binding site | 48-50 | GTP (UniProtKB | ChEBI) | ||||
Sequence: ATA | ||||||
Active site | 64 | GMP-histidine intermediate | ||||
Sequence: H | ||||||
Binding site | 65-68 | GTP (UniProtKB | ChEBI) | ||||
Sequence: RHDR | ||||||
Binding site | 79 | GTP (UniProtKB | ChEBI) | ||||
Sequence: E | ||||||
Binding site | 101 | GTP (UniProtKB | ChEBI) | ||||
Sequence: D |
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | adenosylcobinamide kinase (ATP-specific) activity | |
Molecular Function | adenosylcobinamide kinase (GTP-specific) activity | |
Molecular Function | ATP binding | |
Molecular Function | cobinamide phosphate guanylyltransferase activity | |
Molecular Function | GTP binding | |
Biological Process | cobalamin biosynthetic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameBifunctional adenosylcobalamin biosynthesis protein
- EC number
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Betaproteobacteria > Burkholderiales > Sphaerotilaceae > Methylibium
Accessions
- Primary accessionW7W7R7
Proteomes
Structure
Sequence
- Sequence statusComplete
- Length197
- Mass (Da)21,197
- Last updated2014-04-16 v1
- Checksum145806EC24C586CB
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AZSN01000123 EMBL· GenBank· DDBJ | EWS58591.1 EMBL· GenBank· DDBJ | Genomic DNA |