W7W7R7 · W7W7R7_9BURK

  • Protein
    Bifunctional adenosylcobalamin biosynthesis protein
  • Gene
    cobP_3
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Pathway

Cofactor biosynthesis; adenosylcobalamin biosynthesis; adenosylcobalamin from cob(II)yrinate a,c-diamide: step 5/7.
Cofactor biosynthesis; adenosylcobalamin biosynthesis; adenosylcobalamin from cob(II)yrinate a,c-diamide: step 6/7.

Features

Showing features for binding site, active site.

TypeIDPosition(s)Description
Binding site19-26GTP (UniProtKB | ChEBI)
Binding site48-50GTP (UniProtKB | ChEBI)
Active site64GMP-histidine intermediate
Binding site65-68GTP (UniProtKB | ChEBI)
Binding site79GTP (UniProtKB | ChEBI)
Binding site101GTP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Molecular Functionadenosylcobinamide kinase (ATP-specific) activity
Molecular Functionadenosylcobinamide kinase (GTP-specific) activity
Molecular FunctionATP binding
Molecular Functioncobinamide phosphate guanylyltransferase activity
Molecular FunctionGTP binding
Biological Processcobalamin biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Bifunctional adenosylcobalamin biosynthesis protein
  • EC number

Gene names

    • Name
      cobP_3
    • ORF names
      Y694_03529

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • T29-B
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Betaproteobacteria > Burkholderiales > Sphaerotilaceae > Methylibium

Accessions

  • Primary accession
    W7W7R7

Proteomes

Family & Domains

Features

Showing features for region.

TypeIDPosition(s)Description
Region1-24Disordered

Sequence similarities

Belongs to the CobU/CobP family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    197
  • Mass (Da)
    21,197
  • Last updated
    2014-04-16 v1
  • Checksum
    145806EC24C586CB
MGERRGHPKGSGTGELILGGQRSGKSRCAESRAADWLALPGRSAVLLATALAGDDEMRSRIARHRHDRAERVPGLATDEVPRELAAAVRRHSEPDRMVLVDCLSLWLTNLRMPMQGAAVTDAELDRHVADLCEALRSARGPVVLVSNEIGLGLAPLGAEARRFVDDLGRLHQAVAAQCARVTLMVAGIELPVRRADP

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AZSN01000123
EMBL· GenBank· DDBJ
EWS58591.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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