W7N466 · FDB3_GIBM7

Function

function

Transcription factor; part of the Fusarium detoxification of benzoxazolinone cluster 2 (FDB2) involved in the degradation of benzoxazolinones produced by the host plant (PubMed:19302487, PubMed:26808652).
Maize, wheat, and rye produce the 2 benzoxazinone phytoanticipins 2,4-dihy-droxy-7-methoxy-1,4-benzoxazin-3-one (DIMBOA) and 2,4-dihydroxy-1,4-benzoxazin-3-one (DIBOA) that, due to their inherent instability once released, spontaneously degrade to the more stable corresponding benzoxazolinones, 6-methoxy-2-benzoxazolinone (MBOA) and 2-benzoxazolinone (BOA), respectively (PubMed:11876429).
FDB3 is not essentiel, but contributes to efficient BOA biotransformation (PubMed:19302487).

Miscellaneous

Fusarium verticillioides possesses 2 unlinked loci, FDB1 and FDB2, necessary for detoxification of antimicrobial compounds produced by maize, including 2-benzoxazolinone (BOA) (Probable). The FDB2 cluster arose as a duplication of the FDB1 cluster with rearrangement and expansion by incorporating additional genes (Probable).

Features

Showing features for dna binding.

1748100200300400500600700
TypeIDPosition(s)Description
DNA binding32-59Zn2-C6 fungal-type

GO annotations

AspectTerm
Cellular Componentnucleus
Molecular FunctionDNA-binding transcription factor activity, RNA polymerase II-specific
Molecular FunctionRNA polymerase II cis-regulatory region sequence-specific DNA binding
Molecular Functionzinc ion binding
Biological ProcessDNA-templated transcription
Biological Processpositive regulation of transcription from RNA polymerase II promoter by galactose

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Transcription factor FBD3
  • Alternative names
    • Fusarium detoxification of benzoxazolinone cluster 2 protein 3
      (FDB2 cluster protein 3
      )

Gene names

    • Name
      FDB3
    • ORF names
      FVEG_12635

Organism names

Accessions

  • Primary accession
    W7N466
  • Secondary accessions
    • B6S1X9
    • W7MTI9
    • W7N2Q0

Proteomes

Organism-specific databases

Subcellular Location

Keywords

Phenotypes & Variants

Disruption phenotype

Decreases, but does not eliminate the ability to metabolize 2-benzoxasolinone (BOA).

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00004546031-748Transcription factor FBD3

Expression

Induction

Expression is induced in response to 2-benzoxasolinone (BOA) exposure.

Family & Domains

Features

Showing features for region, compositional bias.

TypeIDPosition(s)Description
Region1-26Disordered
Compositional bias7-22Polar residues
Region116-160Disordered
Compositional bias136-150Polar residues
Region417-438Disordered

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    748
  • Mass (Da)
    82,410
  • Last updated
    2014-04-16 v1
  • Checksum
    373249F9CCD7F632
MPEQPRRPSDQEQNQSETGPPTNKRRRIGLACNACRSRKSRCDGQRPSCSSCLSLGFDCMYEPGDSATNVIVRKDYVTDLEQRVSSVEHNLQRLNDVLKGHLSPCTNANTSPCHHGTINAGPSMPSPAPTAPTKASAPSGARTGTCATSLEEPQDEEGIPNGMAMTFVEEKTSAFYGEASNINFTQLLLRAIAVAHDSPGAPSGLDRASVLGESVVASVSQSKSSLGGTATPFDSLPTALPSVEEMDTLLDLYFDTAGVVFPFIHEETMRKTYNECRLNGFTRARRTWLGTLNMVFAMASNFDRDYTTSSKKRFERSNIFYKRAMGLCNELSKRVISLEIVHYLILVVLHCQGTSRSVQAWNNYGLVIRSAMALGLHAESTERALNPVQKEYRRRTWVVIYCLDKVLSTAVGRPASIPDEQMMRREPSSGRSPATSGNAADLPGDFLAVSFRMYQVMSKSLVIQYGANLDHDSELDEMAHLKASGELRKQLRLWAANLPPHLQLCDVESDVLLQNTKANRLRVILTMRYHNLSILIHKPLLSATILHLFRQGDAANDASSYLIQLAMAEAHECIRSAQLTIDIVHSVITVDATSKNNLGVWYFTLYYVFTASLVICGRLLWAQHGDTVVDEASASHMRFLLGKAETIFLNLDHENSLVLSCLEYVRRLSRMCGIRETGPDAASASIHDNGSNSTGSADAMSFDLDNMDPFQLFASEMFDPAIFDHFNQSPVDGMSFVNGLWDGFPCGG

Sequence caution

The sequence ACE00535.1 differs from that shown. Reason: Erroneous gene model prediction
The sequence EWG54415.1 differs from that shown. Reason: Erroneous gene model prediction
The sequence EWG54416.1 differs from that shown. Reason: Erroneous gene model prediction

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias7-22Polar residues
Compositional bias136-150Polar residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
EU567121
EMBL· GenBank· DDBJ
ACE00535.1
EMBL· GenBank· DDBJ
Genomic DNA Sequence problems.
CM000580
EMBL· GenBank· DDBJ
EWG54414.1
EMBL· GenBank· DDBJ
Genomic DNA
CM000580
EMBL· GenBank· DDBJ
EWG54415.1
EMBL· GenBank· DDBJ
Genomic DNA Sequence problems.
CM000580
EMBL· GenBank· DDBJ
EWG54416.1
EMBL· GenBank· DDBJ
Genomic DNA Sequence problems.

Genome annotation databases

Similar Proteins

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