W6UWB0 · W6UWB0_ECHGR

Function

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Cofactor

Mn2+ (UniProtKB | Rhea| CHEBI:29035 )

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentchromosome
Cellular Componentlipid droplet
Cellular ComponentMre11 complex
Molecular Function1-phosphatidylinositol binding
Molecular Function3'-5'-DNA exonuclease activity
Molecular FunctionDNA endonuclease activity
Molecular Functionmanganese ion binding
Molecular Functionnucleic acid binding
Molecular Functionphosphatidylinositol-3,4,5-trisphosphate binding
Molecular Functionphosphatidylinositol-3,4-bisphosphate binding
Molecular Functionphosphatidylinositol-3-phosphate binding
Molecular Functionzinc ion binding
Biological Processdouble-strand break repair
Biological Processlipid droplet formation
Biological Processmeiotic cell cycle

Keywords

Names & Taxonomy

Protein names

  • Submitted names
    • Zinc finger FYVE domain-containing protein

Gene names

    • ORF names
      EGR_07419

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Spiralia > Lophotrochozoa > Platyhelminthes > Cestoda > Eucestoda > Cyclophyllidea > Taeniidae > Echinococcus > Echinococcus granulosus group

Accessions

  • Primary accession
    W6UWB0

Proteomes

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for signal, chain.

Type
IDPosition(s)Description
Signal1-25
ChainPRO_500488241226-1759

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain, region, compositional bias.

Type
IDPosition(s)Description
Domain526-568FYVE-type
Region567-596Disordered
Domain636-680FYVE-type
Region1350-1387Disordered
Compositional bias1351-1365Polar residues

Sequence similarities

Belongs to the MRE11/RAD32 family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    1,759
  • Mass (Da)
    193,587
  • Last updated
    2014-04-16 v1
  • Checksum
    933CCDD1D1DFEE49
MPRGSANYSALVLFIGVYTLGMTCALPDPDQDALMKESPSEHVVTPPKSVKIIDANENFLFDDSVALAHALGCPPEMKLKTLAIVGNTGDGKSHTLNRAFCLEGAGDGAEDVFFTSSSQSNCTLGVWAAFEPQRGYLLLDTEGLLGTSANPNRQRRLLLKVFAVADVVVYRSMSDRLHTDMFTFLADASDAFVRHFQPHLEALAQQYELPWSARQLGPAVLIFQETRHTLPLVDDADGTAFLKKRFASIHRNVDAFSNLRYVGIQTASGSTNFSPFVRVADELMLETSVRAPRRLEHIFRALLGLSQHFANDLPDAAATAATTLTFVQEYFTCPARCTVCHARCELGVNHTGVPHQSRTRDLGDGCEYSPLLQNKIYYCKRCYAMGRPIVLVPKALEERENAVTGVMKYLWWGYVLSCPHHGVVYRSRAHWSGNPPPEDSPQIHWQVVHLWPGETSLLQGAHPFGQLVVDGLTSVSEQVSQLAGPPTRLLSDFIADSVAPAYWQPNSQIINYTAGAKVSPTDDAEKHHCRACGRGVCDSCSKHRIPVPDRGYVEAAVRVCDRCYASKTHSNGSSSASTAMASRYSGSPDIPRSSAGTSSRRVFELLSATAGYIAPVFSTPKQLVKAAVRPDYWQPDEECTQCVLCGGAFGARLSIHHCRACGRGVCAGCSSRRQPVPQRGLDWPNRGLDNTFRILLTSDNHVGYMEKDGIRGSDTFKTLEEILCLGQEHKVDFILQGGDLFHEVRPSIRCLNEVLRLFRTHCLDESPVQFELLSNPALIFANTSYPGVNYLDLNLNIGLPIFAIHGNHDDPSGFGSVCPPDLLHTCGFINLFGKFDSVEELEVSPLLFRKGSTNLAIYGIGAIREERLHRLFRDNKITFLRPDQGEWFSIAVIHQNRVRHGPTGYLPENFLPSFLDLVVWGHEHSCRIEPEWNGTGNFYVIQPGSSVATSLSEGEAVEKCAGLLEIRDMEFKLTKLPLRSVRRFVFEEVVLKDELSEVDVNSPDVGLRVEQLCTARIQAAIDQAVVVTAESRQQERVVKAEEGASEAMIFKQPSEPLVRLRVDTSGGFERFSALRFGQKFVGRVANPKDLITFTTKRDDATCRGTAINTTAFSQPGTGLNSATERGGFSVNDVEFFISRYFASNSKLQLELLTEVEMATALRHFVIGADNEAIHTTVAKMMAQTRGHLAEVRCGEEEIIPEVMRFANIRRKAEVDDKAASGAPLVVSVFMPGASNVTQPKLVCVEIVYLAGIVKKMAQMFGAKLTLLDLIRPPMHESTPSASVIDAGSVKTESIEEAISDTSVSTRRRLKRITSPFVATSSDESRGETEDQMLLNIIEEVSEDGENVFRTGCDRPSSSAHSISEKQNSTGRRRGGGRRGFGGKAPRRGFGLTRRAAAAIPEISDTEAICIDSGESNDFGEISFDLRRKRVVDFTDRLNPRSRVPHSSGKSEFYCSTCDVPLYSQVNFDIHVKGKKHIDRQKQVLGSRGQGIYVVEGGDDPYKGATFTKPSINALNRVPSNSSNINLNDSTSALFCSVCNLQLNSKSQLEAHMDGKKHRNKASYCIEKVNNSSPSNLHYLNTVPSDAVTNIPSVKDFVPSNSTLCSVCDVPVGIASMGLHEMGRTHIFKSAMANCSRLRFLTEISQSDTDIVLQMPFEDSASITSISLAIALGLVQENRATIDQPSDHCFAVWICSQKLAVSRRMGDVRLLLKNLTNNRPRLVNIVKDTFSMDDRSCGITQHEIAFSTPDVGTLHPTGHP

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias1351-1365Polar residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
APAU02000076
EMBL· GenBank· DDBJ
EUB57759.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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