W6JNN3 · W6JNN3_ATHRO
- Proteinprotein-tyrosine-phosphatase
- Genecdc25
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids494 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
Catalytic activity
- O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Cellular Component | nucleus | |
Molecular Function | protein tyrosine phosphatase activity | |
Biological Process | cell division | |
Biological Process | G2/M transition of mitotic cell cycle | |
Biological Process | positive regulation of G2/M transition of mitotic cell cycle | |
Biological Process | positive regulation of G2/MI transition of meiotic cell cycle | |
Biological Process | protein dephosphorylation |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameprotein-tyrosine-phosphatase
- EC number
Gene names
Organism names
- Organism
- Taxonomic lineageEukaryota > Metazoa > Ecdysozoa > Arthropoda > Hexapoda > Insecta > Pterygota > Neoptera > Endopterygota > Hymenoptera > Tenthredinoidea > Athaliidae > Athalia
Accessions
- Primary accessionW6JNN3
Subcellular Location
UniProt Annotation
GO Annotation
Structure
Family & Domains
Features
Showing features for compositional bias, region, domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 1-43 | Polar residues | ||||
Sequence: MASRRLSSPENVLTPSSTDKENGVVSSPISFNTSPQKFSTLRS | ||||||
Region | 1-70 | Disordered | ||||
Sequence: MASRRLSSPENVLTPSSTDKENGVVSSPISFNTSPQKFSTLRSMKSRVPLEDCDPNSQDSGYGASYPDKD | ||||||
Region | 87-127 | Disordered | ||||
Sequence: APRRLSVESRSPLRSPLRSPVRSNRPPLFRSLSSGSESMDD | ||||||
Compositional bias | 112-126 | Polar residues | ||||
Sequence: PPLFRSLSSGSESMD | ||||||
Region | 159-195 | Disordered | ||||
Sequence: NKSMECEPTTPETRTKPSFRRSLSLQNENITPQSSRV | ||||||
Region | 209-243 | Disordered | ||||
Sequence: TSRLSYNDSPRLVSSPVSPPPKSFKRPEPPSDASP | ||||||
Compositional bias | 222-236 | Pro residues | ||||
Sequence: SSPVSPPPKSFKRPE | ||||||
Domain | 334-447 | Rhodanese | ||||
Sequence: SVRSYKIVDCRYPYEFEGGHVNGALNLFNKDMIEQELLAPLKNVPEIHSDNEKRDIIVFHCEFSWERGPNLSRFLRNIDRQRNKEHYPALHYPEVYLLHGGYQQFYLEEQSLCS |
Sequence similarities
Belongs to the MPI phosphatase family.
Family and domain databases
Sequence
- Sequence statusComplete
- Length494
- Mass (Da)55,587
- Last updated2014-04-16 v1
- Checksum9462D396260E859B
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 1-43 | Polar residues | ||||
Sequence: MASRRLSSPENVLTPSSTDKENGVVSSPISFNTSPQKFSTLRS | ||||||
Compositional bias | 112-126 | Polar residues | ||||
Sequence: PPLFRSLSSGSESMD | ||||||
Compositional bias | 222-236 | Pro residues | ||||
Sequence: SSPVSPPPKSFKRPE |
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AB910531 EMBL· GenBank· DDBJ | BAO51656.1 EMBL· GenBank· DDBJ | Genomic DNA |