W5P7H2 · W5P7H2_SHEEP
- ProteinAmmonium transporter Rh type B
- GeneRHBG
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids463 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
Catalytic activity
- CO2(out) = CO2(in)This reaction proceeds in the forward direction.
- NH4+(in) = NH4+(out)This reaction proceeds in the forward and the backward directions.
- methylamine(out) = methylamine(in)This reaction proceeds in the forward direction.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | basolateral plasma membrane | |
Cellular Component | lateral plasma membrane | |
Molecular Function | ammonium channel activity | |
Biological Process | ammonium homeostasis |
Names & Taxonomy
Protein names
- Recommended nameAmmonium transporter Rh type B
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Laurasiatheria > Artiodactyla > Ruminantia > Pecora > Bovidae > Caprinae > Ovis
Accessions
- Primary accessionW5P7H2
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Basolateral cell membrane ; Multi-pass membrane protein
Cell membrane ; Multi-pass membrane protein
Lateral cell membrane ; Multi-pass membrane protein
Membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 67-85 | Helical | ||||
Sequence: VHAMIFVGFGFLMVFLQRY | ||||||
Transmembrane | 92-111 | Helical | ||||
Sequence: FTFLLAAFALQWSTLIQGFF | ||||||
Transmembrane | 160-182 | Helical | ||||
Sequence: LLLMALLEVVLFGLNEFVLLSLL | ||||||
Transmembrane | 188-209 | Helical | ||||
Sequence: GGSMTIHTFGAYFGLILSRVLY | ||||||
Transmembrane | 221-241 | Helical | ||||
Sequence: GSTYHSDLFAMIGTIFLWIFW | ||||||
Transmembrane | 261-281 | Helical | ||||
Sequence: NTYYSLAASTLSTFALSALVG | ||||||
Transmembrane | 312-333 | Helical | ||||
Sequence: PFGALAAGFLAGAISTLGYKFV | ||||||
Transmembrane | 402-423 | Helical | ||||
Sequence: LFALFVTLTFASVGGGLGGLLL |
Keywords
- Cellular component
PTM/Processing
Features
Showing features for signal, chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Signal | 1-27 | |||||
Sequence: MAWSPRRSAGRGLQLPLLCLLLQGATA | ||||||
Chain | PRO_5004868698 | 28-463 | Ammonium transporter Rh type B | |||
Sequence: ILFAVFVRYNRETDAALWHWGNHSNADNEFYFRYPSFQDVHAMIFVGFGFLMVFLQRYGFSSVGFTFLLAAFALQWSTLIQGFFHSFRGGYILVGMERYPACSCCLISSPILDPHLPLGPLLFKSCWAPSVQLLLMALLEVVLFGLNEFVLLSLLEVKDAGGSMTIHTFGAYFGLILSRVLYRPHLEKSKHRQGSTYHSDLFAMIGTIFLWIFWPSFNSAPTALGDGQHRTALNTYYSLAASTLSTFALSALVGGDGRLDMVHVQNAALAGGVVVGTSAEMMLTPFGALAAGFLAGAISTLGYKFVTPILESKLKVQDTCGVHNLHGMPGVLGALLGSLVAGLATSEAYGDGLESVFPLIAEGQRSATSQAMHQLFALFVTLTFASVGGGLGGLLLRLPILDSPPDSQCYEDQIYWEVPGEHEHLAQGSQEIETQA |
Keywords
- PTM
Proteomic databases
Expression
Gene expression databases
Interaction
Subunit
Interacts (via C-terminus) with ANK2 and ANK3; required for targeting to the basolateral membrane.
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 26-427 | Ammonium transporter AmtB-like | ||||
Sequence: TAILFAVFVRYNRETDAALWHWGNHSNADNEFYFRYPSFQDVHAMIFVGFGFLMVFLQRYGFSSVGFTFLLAAFALQWSTLIQGFFHSFRGGYILVGMERYPACSCCLISSPILDPHLPLGPLLFKSCWAPSVQLLLMALLEVVLFGLNEFVLLSLLEVKDAGGSMTIHTFGAYFGLILSRVLYRPHLEKSKHRQGSTYHSDLFAMIGTIFLWIFWPSFNSAPTALGDGQHRTALNTYYSLAASTLSTFALSALVGGDGRLDMVHVQNAALAGGVVVGTSAEMMLTPFGALAAGFLAGAISTLGYKFVTPILESKLKVQDTCGVHNLHGMPGVLGALLGSLVAGLATSEAYGDGLESVFPLIAEGQRSATSQAMHQLFALFVTLTFASVGGGLGGLLLRLPI |
Sequence similarities
Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length463
- Mass (Da)50,256
- Last updated2014-04-16 v1
- Checksum102FA1B55CDF10B0
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AMGL01004882 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. |