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W5ML37 · W5ML37_LEPOC

Function

Catalytic activity

  • Couples ATP hydrolysis with the unwinding of duplex DNA by translocating in the 3'-5' direction.
    EC:5.6.2.4 (UniProtKB | ENZYME | Rhea)

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Molecular FunctionATP binding
Molecular Functionnucleic acid binding
Molecular Functionzinc ion binding

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    DNA 3'-5' helicase
  • EC number

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Holostei > Semionotiformes > Lepisosteidae > Lepisosteus

Accessions

  • Primary accession
    W5ML37

Proteomes

Expression

Gene expression databases

Family & Domains

Features

Showing features for region, compositional bias, domain.

Type
IDPosition(s)Description
Region51-81Disordered
Compositional bias60-81Polar residues
Region135-181Disordered
Compositional bias137-151Polar residues
Compositional bias158-181Polar residues
Region333-490Disordered
Compositional bias369-421Basic and acidic residues
Compositional bias428-460Basic and acidic residues
Compositional bias475-489Polar residues
Domain546-560CCHC-type
Region619-638Disordered
Domain670-848Helicase ATP-binding
Domain871-1075Helicase C-terminal
Region1094-1115Disordered

Sequence similarities

Belongs to the helicase family. RecQ subfamily.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    1,437
  • Mass (Da)
    160,960
  • Last updated
    2014-04-16 v1
  • MD5 Checksum
    75E32720C6432B15B37858C407B1438E
MDRYNELKMLLKNWELTFVQENKRKPTKDDIDRASEETKNLYREYRELKQAREEGSVGKSCKENSGNVGQNPTTTGQSEKEMDCWGSHLNRKNMPVSTQRLTPKDSDALKASAQYFGMKLKSNLGASIKDRPFSLKKSFTPKTTPLKSLKEGSSPRASMGPATPQLKPANTSPNLSTSAETSVHEESEELFAPIPGFTPSKKAHLLRESITKRLSSVDKGWLERCQVFDEVEKTEKPVTGNLLSPAGEGMLPLTEANRNVAHPSLSAAAAQQNSALLGETASKEEPLTVEGSVQLSNGLSASEMDTSARSECTFTFKDNVKEKEGETRLTLKEDCGNESGLPSACVAAKESKKEVSYKELPSQDRYSPVKSDTGRRETEKRSRKRQREPGAGGEKPAELPEEGTAKKKRKTRRETSGSPKSPRVKKSHARPSQREDGEKEETSGSERKKQKQKIPTENLLGETEEEIPVSTRVQNKVRPRASSNKDGNFVKINLKKKSHVKGYALKGAFLRKQLYMEKFQLKGERFGGGGGRRGRWARAGHGGDSCFKCGGTGHWARDCRGRAPAPAVENESAEEADAEPFELPTLEEVARATSTLRSDGQEAESQVKEEDDVLLNVVRPDYEKPSPPPSMEPLYSLGEDGKVRDVPEEVYEALRDFGYKSFRPGQEVAIMRILSGLSTLVVLSTGMGKSLCYQLPAYLYAKRSKSIALVVSPLVSLMDDQLSGLPPKLKAVCIHSNMTQKQREAAIKKVKDGQVHVLLLSPEALVGGGHGGSGCLPPADQLPPVAFACIDEAHCVSEWSHNFRPCYLRLCKVLRDRLGVRCLLGLTATATLATALDIAQHLDIRDREGIAVRSAAVPPNLQLSVSMDRDKDQSLVSLLKGERFGSLDSVIVYCTRREETTRISALLRTCLQGVMLRESSRPLSGETEEDTPGKRIKASTKKKIRKPLKWIAESYHAGLSAAQRRRVQNNFMCGELRIVVATVAFGMGLDKSDVRGIIHYNMPKSFESYVQEIGRAGRDGEPAHCHLFLDPEGRDLHELRRHIYADTVDYFTVKKLVQKAFPPCKCRQIHQKQLSMMQAGEVDDQEMLELADPPVDASPEQEEQKPETNENDQPVSRVCLTHERAIPIQETVETLDITEEGIETMLCYLELHPQQWVELLHPTLSSCRLVCYGGPQQLRKLTKICPPVAVTLARMRLSGVHVEHCSSVEFDVVELADTMGWELVPVKRGLRQLQWSMQSGFHGSSGTGRSGVLVEFSNLSFHFRSYGDLTPEELDGVCEFLHRRVLAQERTQLYQLKACFKAFRSVAYRNCSFCTDEMDEERSLKLKKLLRDYFDEKMDLDLSKKYEEDKEKEDEELSESKLKDWEDQIRADIRSFLSCHSDEKFSGRAVARVFHGIGSPCYPAQTFGKDRRFWRKYLHFDFNEIIRMATQEIIRTK

Computationally mapped potential isoform sequences

There is 1 potential isoform mapped to this entry

View all
EntryEntry nameGene nameLength
W5ML25W5ML25_LEPOC1459

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias60-81Polar residues
Compositional bias137-151Polar residues
Compositional bias158-181Polar residues
Compositional bias369-421Basic and acidic residues
Compositional bias428-460Basic and acidic residues
Compositional bias475-489Polar residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AHAT01018149
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.

Genome annotation databases

Similar Proteins

Disclaimer

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