W2T514 · W2T514_NECAM
- ProteinGuanylate cyclase
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids966 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
Catalytic activity
- GTP = 3',5'-cyclic GMP + diphosphate
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | plasma membrane | |
Molecular Function | adenylate cyclase activity | |
Molecular Function | ATP binding | |
Molecular Function | guanylate cyclase activity | |
Molecular Function | peptide receptor activity | |
Molecular Function | protein kinase activity | |
Biological Process | intracellular signal transduction | |
Biological Process | protein phosphorylation | |
Biological Process | receptor guanylyl cyclase signaling pathway |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameGuanylate cyclase
- EC number
Gene names
Organism names
- Taxonomic lineageEukaryota > Metazoa > Ecdysozoa > Nematoda > Chromadorea > Rhabditida > Rhabditina > Rhabditomorpha > Strongyloidea > Ancylostomatidae > Bunostominae > Necator
Accessions
- Primary accessionW2T514
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Membrane ; Single-pass type I membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Transmembrane | 223-246 | Helical | |||
Keywords
- Cellular component
PTM/Processing
Keywords
- PTM
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for region, compositional bias, domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Region | 271-316 | Disordered | |||
Compositional bias | 296-316 | Polar residues | |||
Region | 370-392 | Disordered | |||
Domain | 411-703 | Protein kinase | |||
Domain | 776-905 | Guanylate cyclase | |||
Sequence similarities
Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length966
- Mass (Da)109,498
- Last updated2014-03-19 v1
- MD5 Checksum9E7FD11AAEBC050CFFB709233369EE87
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 296-316 | Polar residues | |||
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
KI660254 EMBL· GenBank· DDBJ | ETN76062.1 EMBL· GenBank· DDBJ | Genomic DNA |