W2PDG1 · XLP1_PHYN3
- ProteinInactive glycoside hydrolase XLP1
- GeneXLP1
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids238 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score4/5
Function
function
Non-functional secreted XEG1-like protein that binds to host Nicotiana benthamiana apoplastic glucanase inhibitor protein GIP2 more tightly than does XEG1, thus it outcompetes XEG1 for GIP2 binding and frees functional XEG1 to support P.parasitica infection (PubMed:28082413).
With XEG1, is required to elevate apoplastic sugar during P.parasitica infection (PubMed:28082413).
With XEG1, is required to elevate apoplastic sugar during P.parasitica infection (PubMed:28082413).
Features
Showing features for active site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Active site | 133 | |||||
Sequence: E | ||||||
Active site | 219 | |||||
Sequence: E |
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | extracellular region | |
Molecular Function | cellulase activity | |
Biological Process | polysaccharide catabolic process |
Keywords
- Molecular function
- Biological process
Names & Taxonomy
Protein names
- Recommended nameInactive glycoside hydrolase XLP1
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Sar > Stramenopiles > Oomycota > Peronosporales > Peronosporaceae > Phytophthora
Accessions
- Primary accessionW2PDG1
Proteomes
Organism-specific databases
Subcellular Location
Phenotypes & Variants
Features
Showing features for mutagenesis.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Mutagenesis | 25 | Affects the binding to host GIP2 and relieves GIP2 inhibition of XEG1-induced sugar elevation; when associated with A-39, A-41, A-42, A-43, A-44, A-77 and A-78. | ||||
Sequence: W → A | ||||||
Mutagenesis | 38 | Affects the binding to host GIP2 and relieves GIP2 inhibition of XEG1-induced sugar elevation; when associated with A-26, A-41, A-42, A-43, A-44, A-77 and A-78. | ||||
Sequence: N → A | ||||||
Mutagenesis | 40 | Affects the binding to host GIP2 and relieves GIP2 inhibition of XEG1-induced sugar elevation; when associated with A-26, A-39, A42, A-43, A-44, A-77 and A-78. | ||||
Sequence: W → A | ||||||
Mutagenesis | 41 | Affects the binding to host GIP2 and relieves GIP2 inhibition of XEG1-induced sugar elevation; when associated with A-26, A-39, A-41, A-43, A-44, A-77 and A-78. | ||||
Sequence: N → A | ||||||
Mutagenesis | 42 | Affects the binding to host GIP2 and relieves GIP2 inhibition of XEG1-induced sugar elevation; when associated with A-26, A-39, A-41, A-42, A-44, A-77 and A-78. | ||||
Sequence: Q → A | ||||||
Mutagenesis | 43 | Affects the binding to host GIP2 and relieves GIP2 inhibition of XEG1-induced sugar elevation; when associated with A-26, A-39, A-41, A-42, A-43, A-77 and A-78. | ||||
Sequence: N → A | ||||||
Mutagenesis | 75 | Affects the binding to host GIP2 and relieves GIP2 inhibition of XEG1-induced sugar elevation; when associated with A-26, A-39, A-41, A-42, A-43, A-44 and A-78. | ||||
Sequence: T → A | ||||||
Mutagenesis | 76 | Affects the binding to host GIP2 and relieves GIP2 inhibition of XEG1-induced sugar elevation; when associated with A-26, A-39, A-41, A-42, A-43, A-44 and A-77. | ||||
Sequence: Q → A |
PTM/Processing
Features
Showing features for signal, chain, glycosylation.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Signal | 1-19 | |||||
Sequence: MKSFLIAIVIAVLLPVSAA | ||||||
Chain | PRO_5004821942 | 20-238 | Inactive glycoside hydrolase XLP1 | |||
Sequence: DFCAQWRLSKAGKYIIYNNLWNQNTATSGSQCTGVDKVSGSTVAWHTSYSWAGAPTQVKSYSNAALVFTKKQIKNIKTIPTTMKYSYSYSGTLIADVAYDLFTSSTASGSNEYEIMIWLAAYGGAGPISSTGKAIATVTINSNSFKLYKGPNGSTTVYSFVATKTITNFSADLLDFFTYLVKTQAFPSSQYLTTLEAGTEPFTGSNAKMTVSSYSAAVN | ||||||
Glycosylation | 171 | N-linked (GlcNAc...) asparagine | ||||
Sequence: N | ||||||
Glycosylation | 187 | N-linked (GlcNAc...) asparagine | ||||
Sequence: N |
Keywords
- PTM
PTM databases
Interaction
Subunit
Interacts with host apoplastic glucanase inhibitor GIP2.
Protein-protein interaction databases
Structure
Sequence
- Sequence statusComplete
- Sequence processingThe displayed sequence is further processed into a mature form.
- Length238
- Mass (Da)25,545
- Last updated2014-03-19 v1
- Checksum65F8BA5CC9C5A2D8
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
KI669674 EMBL· GenBank· DDBJ | ETM98685.1 EMBL· GenBank· DDBJ | Genomic DNA |