W0ZD75 · W0ZD75_9MICO

Function

function

Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Protein has several cofactor binding sites:
Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

thiamine diphosphate (UniProtKB | Rhea| CHEBI:58937 )

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site239Mg2+ (UniProtKB | ChEBI)
Binding site269Mg2+ (UniProtKB | ChEBI)
Binding site271Mg2+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Molecular Functionmagnesium ion binding
Molecular Functionpyruvate dehydrogenase (acetyl-transferring) activity

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Pyruvate dehydrogenase E1 component
  • EC number

Gene names

    • Name
      aceE
    • ORF names
      MIC448_550007

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • C448
  • Taxonomic lineage
    Bacteria > Actinomycetota > Actinomycetes > Micrococcales > Microbacteriaceae > Microbacterium

Accessions

  • Primary accession
    W0ZD75

Proteomes

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for region, domain.

TypeIDPosition(s)Description
Region1-23Disordered
Domain144-305Transketolase N-terminal
Domain489-710Pyruvate dehydrogenase E1 component middle

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    908
  • Mass (Da)
    100,520
  • Last updated
    2014-03-19 v1
  • Checksum
    BBFCD9DC79EC7AE8
MTVHDQDPYSQNAADSDPEETSEWQESLQQLVDAKGHGRGREVMLSLLKKSHDLHLGVPMVPTTDYINTIAPENEPEFPGDEEIERRYRAWIRWNAAVTVHRAQRPGIGVGGHISTYASSAALYEVGFNHFFRGHDHPSGGDQIFIQGHASPGTYARAFLEGRLTEAQLDGFRQEKSAAPNGIPSYPHPRLMPEFWQFPTVSMGLGPINAIYQAMTNKYLTNRGIKDVSDGHVWAFLGDGEMDEVESRGQLQVAANEGLDNLTFVINANLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGREWDDLLSRDTDGALLNLMNVTPDGDYQTYKTENGAYVRENFFGRDERALALVKDYSDEKIWGLKRGGHDYRKVYAAYKAAVEHKGQPTVIIAKTIKGYGLGKHFEGRNATHQMKKMTLEDLKHFRDEMHIPISDGQLEENPYLPPYYNPGAQDETIQYLLERRRDLGGFLPERRTTHVGLTLPDDSAYTMPKKGSGTQEVATTMAFVRLLKDLLRSKDFGHRIVPIIPDEARTFGMDAFFPTAKIYNPNGQHYTSVDRELLLAYKESPQGQILHVGINEAGALAAFTGVGTSYSTHGEPLIPVYVFYSMFGFQRTGDAQWAAGDQMARGFVVGATAGRTTLTGEGLQHADGHSHLLASTNPATVSYDPAYGYEIAHIVRAGIERMYGGQHPDPNVMYYLTVYNEPIVQPAEPEGVDVDGIVRGIHRISTGEGDGARAQLLASGVGVPWAKEAQQLLRDDWGVAADVWSVTSWTELRRDGLAADEHNFLHPEEEPKTAYITEKLAGAPGPVIAVSDFMHAVQDQIRPWVQHDFYTLGADGFGFSDTRAAARRFFKIDGPSIVVRALQALAQQGAVDRSLVAQAIEKYRLFDVTAGTSGNAGGES

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CBVQ010000220
EMBL· GenBank· DDBJ
CDK01314.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

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