W0Z4B1 · W0Z4B1_9MICO
- ProteinUDP-N-acetylmuramate--L-alanine ligase
- GenemurC
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids470 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Cell wall formation.
Catalytic activity
- ATP + L-alanine + UDP-N-acetyl-alpha-D-muramate = ADP + H+ + phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanine
Pathway
Cell wall biogenesis; peptidoglycan biosynthesis.
Features
Showing features for binding site.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | ATP binding | |
Molecular Function | UDP-N-acetylmuramate-L-alanine ligase activity | |
Biological Process | cell division | |
Biological Process | cell wall organization | |
Biological Process | peptidoglycan biosynthetic process | |
Biological Process | regulation of cell shape |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameUDP-N-acetylmuramate--L-alanine ligase
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Actinomycetota > Actinomycetes > Micrococcales > Microbacteriaceae > Microbacterium
Accessions
- Primary accessionW0Z4B1
Proteomes
Subcellular Location
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 18-112 | Mur ligase N-terminal catalytic | ||||
Sequence: HFIGIGGSGMSGLARMFLARGIRVSGSDRADSDALRQLALLGARVHVGHDAANLGDADTVIHTGAIWPENPEYVLAKERGMPVIHRSQALHWLIG | ||||||
Domain | 119-294 | Mur ligase central | ||||
Sequence: VAGAHGKTTSTGMIITALHELGADPSFVNGGVIAQLGASSGTGVDELFVVEADESDGTFLLYDTSIALITNVDPDHLDHYGTNDAFDDAFARFADAARESVVISADDPGALRVTSRLTHPNVITFGESDGADVRVTDITTDGPVSFALTYRGVTERARLEIPGAHNAINAAGVVAV | ||||||
Domain | 317-447 | Mur ligase C-terminal | ||||
Sequence: RRFELHGVTRGVSVFDDYAHHPTEVAAALAAARTVIGEGRIIAVHQPHTYSRTQQMYREFAEVLEEYADHTVVLDVYGAREDPIPGVTGALVRDAFAAPDHVAYVADWQEAADYTATVAREGDYVITLGCG |
Sequence similarities
Belongs to the MurCDEF family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length470
- Mass (Da)49,849
- Last updated2014-03-19 v1
- ChecksumABE2544B4C823E39
Keywords
- Technical term