W0J3M8 · W0J3M8_9BACT
- ProteinFluoride-specific ion channel FluC
- GenefluC
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids131 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
Catalytic activity
- fluoride(in) = fluoride(out)This reaction proceeds in the forward direction.
Activity regulation
Na+ is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 84 | Na+ (UniProtKB | ChEBI); structural | |||
Binding site | 87 | Na+ (UniProtKB | ChEBI); structural | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | plasma membrane | |
Molecular Function | fluoride channel activity | |
Molecular Function | metal ion binding | |
Biological Process | cellular detoxification of fluoride |
Keywords
- Molecular function
- Biological process
- Ligand
Names & Taxonomy
Protein names
- Recommended nameFluoride-specific ion channel FluC
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Verrucomicrobiota > Opitutia > Opitutales > Opitutaceae
Accessions
- Primary accessionW0J3M8
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Cell membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Transmembrane | 12-32 | Helical | |||
Transmembrane | 44-64 | Helical | |||
Transmembrane | 76-94 | Helical | |||
Transmembrane | 106-127 | Helical | |||
Keywords
- Cellular component
Interaction
Protein-protein interaction databases
Structure
Sequence
- Sequence statusComplete
- Length131
- Mass (Da)13,959
- Last updated2014-03-19 v1
- MD5 Checksum753CBF4DCC20D217F2DCA3F10F45742B
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP007053 EMBL· GenBank· DDBJ | AHF93017.1 EMBL· GenBank· DDBJ | Genomic DNA |