V9KGK5 · V9KGK5_CALMI

Function

Catalytic activity

  • (5Z,8Z,11Z,14Z)-eicosatetraenoate + L-phenylalanine = H2O + N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-L-phenylalanine
    This reaction proceeds in the forward
    and the backward
    directions.
  • (9Z)-octadecenoate + L-phenylalanine = H2O + N-(9Z-octadecenoyl)-L-phenylalanine
    This reaction proceeds in the forward
    and the backward
    directions.
  • (9Z)-octadecenoate + glycine = H2O + N-(9Z-octadecenoyl)glycine
    This reaction proceeds in the backward direction.
  • H2O + N-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-L-phenylalanine = (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + L-phenylalanine
    This reaction proceeds in the forward direction.
  • H2O + N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-glycine = (5Z,8Z,11Z,14Z)-eicosatetraenoate + glycine
    This reaction proceeds in the forward
    and the backward
    directions.
  • H2O + N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-L-serine = (5Z,8Z,11Z,14Z)-eicosatetraenoate + L-serine
    This reaction proceeds in the forward
    and the backward
    directions.
  • H2O + N-(9Z-octadecenoyl)-L-asparagine = (9Z)-octadecenoate + L-asparagine
    This reaction proceeds in the forward direction.
  • H2O + N-(9Z-octadecenoyl)-L-glutamine = (9Z)-octadecenoate + L-glutamine
    This reaction proceeds in the forward direction.
  • H2O + N-(9Z-octadecenoyl)-L-leucine = (9Z)-octadecenoate + L-leucine
    This reaction proceeds in the forward
    and the backward
    directions.
  • H2O + N-(9Z-octadecenoyl)-L-lysine = (9Z)-octadecenoate + L-lysine
    This reaction proceeds in the forward direction.
  • H2O + N-(9Z-octadecenoyl)-L-methionine = (9Z)-octadecenoate + L-methionine
    This reaction proceeds in the forward direction.
  • H2O + N-(9Z-octadecenoyl)-L-serine = (9Z)-octadecenoate + L-serine
    This reaction proceeds in the forward direction.
  • H2O + N-(9Z-octadecenoyl)-L-tryptophan = (9Z)-octadecenoate + L-tryptophan
    This reaction proceeds in the forward direction.
  • H2O + N-(9Z-octadecenoyl)-L-tyrosine = (9Z)-octadecenoate + L-tyrosine
    This reaction proceeds in the forward direction.
  • H2O + N-hexadecanoyl-L-phenylalanine = hexadecanoate + L-phenylalanine
    This reaction proceeds in the forward direction.
  • H2O + N-octadecanoyl-L-phenylalanine = L-phenylalanine + octadecanoate
    This reaction proceeds in the forward direction.
  • an N-acyl-L-amino acid + H2O = a carboxylate + an L-alpha-amino acid
    This reaction proceeds in the forward
    and the backward
    directions.
    EC:3.5.1.14 (UniProtKB | ENZYME | Rhea)
  • an N-acyl-aromatic L-alpha-amino acid + H2O = a carboxylate + an aromatic L-alpha-amino acid
    This reaction proceeds in the forward
    and the backward
    directions.
    EC:3.5.1.114 (UniProtKB | ENZYME | Rhea)

Pathway

Amino-acid metabolism.
Lipid metabolism; fatty acid metabolism.

Features

Showing features for binding site, active site.

TypeIDPosition(s)Description
Binding site165Zn2+ 2 (UniProtKB | ChEBI)
Active site167
Binding site197Zn2+ 2 (UniProtKB | ChEBI)
Binding site197Zn2+ 1 (UniProtKB | ChEBI)
Active site231Proton acceptor
Binding site232Zn2+ 1 (UniProtKB | ChEBI)
Binding site258Zn2+ 2 (UniProtKB | ChEBI)
Binding site504Zn2+ 1 (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentmembrane
Molecular Functionhydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
Molecular Functionmetal ion binding
Molecular Functionmetallocarboxypeptidase activity
Biological Processamide biosynthetic process
Biological Processamide catabolic process
Biological Processamino acid metabolic process
Biological Processcellular lipid metabolic process
Biological Processproteolysis

Keywords

Names & Taxonomy

Protein names

  • Submitted names
    • Peptidase M20 domain-containing 1

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Chondrichthyes > Holocephali > Chimaeriformes > Callorhinchidae > Callorhinchus

Accessions

  • Primary accession
    V9KGK5

Subcellular Location

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane36-57Helical

Keywords

  • Cellular component

PTM/Processing

Features

Showing features for signal, chain.

TypeIDPosition(s)Description
Signal1-20
ChainPRO_500477779721-544

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain281-422Peptidase M20 dimerisation

Sequence similarities

Belongs to the peptidase M20A family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    544
  • Mass (Da)
    60,413
  • Last updated
    2014-03-19 v1
  • Checksum
    7CF5026863F59ABE
MCGLFSVCLALLQCSGLLWAAPAADRCSAEMNRARIVKLTALLVLCAFAVFLVALLIRAHTFQPGSWQLRDCLPNNRTLAANFTPEERDELLSVFKGAIQLPTVSTSYSELNITALKSFTDYLPKAFPGVFSSDLVRHEIIANYSHLFTVRGSDPGLRPYILTAHLDVVPVAEEKWDFPPFSGEESDGYLYGRGTLDDKASAVGILQALEFLLNRGYVPRRAFYVAIGHDEEVGGDNGARNIAATLESRGVKLSFLLDEGSVILDHIIPGLKKPVAVIAVTEKGQALFSLKVNTQTGHSSMPMRESSIGILASAVSRLEKKPMPRMFGLGPELAMFEQLGPEMSFPLNIIMANLWLFAPIISRTLEKNPSMNALVRTTTAVTEFHAGIKPNVLPPTANATLNFRIHPAHSVQGLIEEMRYTIDDDRVKIDLLYGFDPLPTSPHDELAFGYQIIRTTVQNVFPEVFVIPGLSVANTDTRHYQHLTEGLYRFVPLWITQEDTGRIHGPNERISVKNYEEIVRFYFHLIQNSDLNLRLNVHSSGHEL

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JW864442
EMBL· GenBank· DDBJ
AFO96959.1
EMBL· GenBank· DDBJ
mRNA

Similar Proteins

Disclaimer

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