V9KES0 · V9KES0_CALMI
- ProteinSolute carrier family 15 member 1
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids720 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score5/5
Function
Catalytic activity
- 2 H+(out) + L-alanyl-L-aspartate(out) = 2 H+(in) + L-alanyl-L-aspartate(in)This reaction proceeds in the forward direction.
2 H+ (out)CHEBI:15378+ L-alanyl-L-aspartate (out)CHEBI:74363= 2 H+ (in)CHEBI:15378+ L-alanyl-L-aspartate (in)CHEBI:74363 - 2 H+(out) + L-aspartyl-glycine(out) = 2 H+(in) + L-aspartyl-glycine(in)This reaction proceeds in the forward direction.
- 2 H+(out) + N-acetyl-D-muramoyl-L-alanyl-D-isoglutamine(out) = 2 H+(in) + N-acetyl-D-muramoyl-L-alanyl-D-isoglutamine(in)
- 2 H+(out) + N-formyl-L-methionyl-L-leucyl-L-phenylalanine(out) = 2 H+(in) + N-formyl-L-methionyl-L-leucyl-L-phenylalanine(in)
- H+(out) + L-alanyl-L-leucyl-L-alanine(out) = H+(in) + L-alanyl-L-leucyl-L-alanine(in)This reaction proceeds in the forward direction.
- H+(out) + L-alanyl-L-lysine(out) = H+(in) + L-alanyl-L-lysine(in)This reaction proceeds in the forward direction.
- H+(out) + L-alanyl-L-proline(out) = H+(in) + L-alanyl-L-proline(in)This reaction proceeds in the forward direction.
- H+(out) + L-alanyl-L-prolylglycine(out) = H+(in) + L-alanyl-L-prolylglycine(in)This reaction proceeds in the forward direction.
- H+(out) + L-alanyl-L-valine(out) = H+(in) + L-alanyl-L-valine(in)This reaction proceeds in the forward direction.
- H+(out) + L-leucyl-L-leucine(out) = H+(in) + L-leucyl-L-leucine(in)This reaction proceeds in the forward direction.
- H+(out) + L-leucyl-L-proline(out) = H+(in) + L-leucyl-L-proline(in)This reaction proceeds in the forward direction.
- H+(out) + L-lysyl-glycine(out) = H+(in) + L-lysyl-glycine(in)This reaction proceeds in the forward and the backward directions.
- H+(out) + L-methionyl-L-phenylalanyl-L-methionine(out) = H+(in) + L-methionyl-L-phenylalanyl-L-methionine(in)This reaction proceeds in the forward direction.
- H+(out) + L-phenylalanyl-L-leucine(out) = H+(in) + L-phenylalanyl-L-leucine(in)This reaction proceeds in the forward direction.
- H+(out) + L-phenylalanyl-L-phenylalanine(out) = H+(in) + L-phenylalanyl-L-phenylalanine(in)This reaction proceeds in the forward direction.
- H+(out) + L-tyrosylglycine(out) = H+(in) + L-tyrosylglycine(in)This reaction proceeds in the forward direction.
- a dipeptide(out) + H+(out) = a dipeptide(in) + H+(in)This reaction proceeds in the forward direction.
- an L-amino acid tripeptide(out) + H+(out) = an L-amino acid tripeptide(in) + H+(in)This reaction proceeds in the forward direction.
- carnosine(out) + H+(out) = carnosine(in) + H+(in)This reaction proceeds in the forward direction.
- glycyl-L-aspartate(out) + 2 H+(out) = glycyl-L-aspartate(in) + 2 H+(in)This reaction proceeds in the forward and the backward directions.
- glycyl-L-glutamate(out) + 2 H+(out) = glycyl-L-glutamate(in) + 2 H+(in)This reaction proceeds in the forward direction.
- glycyl-L-glutamine(out) + H+(out) = glycyl-L-glutamine(in) + H+(in)This reaction proceeds in the forward and the backward directions.
- glycyl-L-leucine(out) + H+(out) = glycyl-L-leucine(in) + H+(in)This reaction proceeds in the forward direction.
- glycyl-L-proline(out) + H+(out) = glycyl-L-proline(in) + H+(in)This reaction proceeds in the forward direction.
- glycyl-sarcosine(out) + H+(out) = glycyl-sarcosine(in) + H+(in)This reaction proceeds in the forward direction.
- glycylglycyl-L-isoleucine(out) + H+(out) = glycylglycyl-L-isoleucine(in) + H+(in)This reaction proceeds in the forward direction.
- glycylglycyl-L-proline(out) + H+(out) = glycylglycyl-L-proline(in) + H+(in)This reaction proceeds in the forward direction.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | apical plasma membrane | |
Molecular Function | dipeptide transmembrane transporter activity | |
Molecular Function | symporter activity | |
Biological Process | dipeptide import across plasma membrane | |
Biological Process | peptide transport |
Keywords
- Biological process
Names & Taxonomy
Protein names
- Recommended nameSolute carrier family 15 member 1
- Alternative names
Organism names
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Chondrichthyes > Holocephali > Chimaeriformes > Callorhinchidae > Callorhinchus
Accessions
- Primary accessionV9KES0
Subcellular Location
UniProt Annotation
GO Annotation
Apical cell membrane ; Multi-pass membrane protein
Cell membrane ; Multi-pass membrane protein
Membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 36-53 | Helical | ||||
Sequence: FSYYGMRAVLVLYFRYFL | ||||||
Transmembrane | 62-86 | Helical | ||||
Sequence: AIYHAFVALCYFTPILGAIIADSWL | ||||||
Transmembrane | 92-115 | Helical | ||||
Sequence: IIYLSIVYAIGQLVMSIGAIADLT | ||||||
Transmembrane | 127-148 | Helical | ||||
Sequence: LTLHVALSATGLLLIALGTGGI | ||||||
Transmembrane | 174-193 | Helical | ||||
Sequence: IFYLSINAGSLISTIITPVL | ||||||
Transmembrane | 205-226 | Helical | ||||
Sequence: CYPLAFGVPAALMVVALIVFIL | ||||||
Transmembrane | 287-305 | Helical | ||||
Sequence: MVLKVLFLYIPLPMFWALF | ||||||
Transmembrane | 339-356 | Helical | ||||
Sequence: ILILIMVPIFDIVIYPLI | ||||||
Transmembrane | 368-386 | Helical | ||||
Sequence: KITVGMLIAGLAFVVAALL | ||||||
Transmembrane | 626-644 | Helical | ||||
Sequence: QAGWLLTTAFGNIIVLIVA | ||||||
Transmembrane | 656-680 | Helical | ||||
Sequence: YILFASLLGAVSIIFGIMASFYVYV |
Keywords
- Cellular component
Interaction
Subunit
Interacts (via extracellular domain region) with trypsin.
Structure
Family & Domains
Features
Showing features for compositional bias, region.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 691-708 | Basic and acidic residues | ||||
Sequence: EKERAKKKAEDLESHSIH | ||||||
Region | 691-720 | Disordered | ||||
Sequence: EKERAKKKAEDLESHSIHENGNETIAQSKF |
Sequence similarities
Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length720
- Mass (Da)80,283
- Last updated2014-03-19 v1
- Checksum786D82E6CDDC16F4
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 691-708 | Basic and acidic residues | ||||
Sequence: EKERAKKKAEDLESHSIH |