V9K8I9 · V9K8I9_CALMI

Function

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Features

Showing features for binding site.

1930100200300400500600700800900
TypeIDPosition(s)Description
Binding site197Ca2+ (UniProtKB | ChEBI)
Binding site211Ca2+ (UniProtKB | ChEBI)
Binding site252Ca2+ (UniProtKB | ChEBI)

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentaxon
Cellular Componentfocal adhesion
Cellular Componentmembrane
Molecular Functionheparin binding
Molecular Functionmetal ion binding
Molecular Functionsemaphorin receptor activity
Molecular Functionvascular endothelial growth factor binding
Molecular Functionvascular endothelial growth factor receptor activity
Biological Processaxon guidance
Biological Processneural crest cell migration
Biological Processpositive regulation of endothelial cell migration
Biological Processpositive regulation of filopodium assembly
Biological Processregulation of vascular endothelial growth factor receptor signaling pathway
Biological Processresponse to wounding
Biological Processsprouting angiogenesis
Biological Processvascular endothelial growth factor receptor signaling pathway
Biological Processvasculogenesis

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Neuropilin

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Chondrichthyes > Holocephali > Chimaeriformes > Callorhinchidae > Callorhinchus

Accessions

  • Primary accession
    V9K8I9

Subcellular Location

Membrane
; Single-pass type I membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane864-889Helical

Keywords

  • Cellular component

PTM/Processing

Features

Showing features for signal, chain, disulfide bond.

TypeIDPosition(s)Description
Signal1-23
ChainPRO_500477850924-930Neuropilin
Disulfide bond29↔56
Disulfide bond84↔106
Disulfide bond149↔175
Disulfide bond208↔230
Disulfide bond277↔426
Disulfide bond433↔585

Keywords

Family & Domains

Features

Showing features for domain, region.

TypeIDPosition(s)Description
Domain29-143CUB
Domain149-267CUB
Domain277-426F5/8 type C
Domain433-585F5/8 type C
Domain652-817MAM
Region831-854Disordered

Sequence similarities

Belongs to the neuropilin family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    930
  • Mass (Da)
    103,875
  • Last updated
    2014-03-19 v1
  • Checksum
    0F9D0AB95488F15A
MRKQRRTAALLHTLTVLIGLSGAHRSDRCGDTIHITSPGYLSSPGYPNSYYPRESCAWTIQAPQPYQRIMINFNPHFDLEDRDCKYDYVEVRDGGDEKAALLGKFCGKIAPSPQISTGPLLFVKFVSDYETHGAGFSIRYEVFKTGPECSRNYTSQSAEIRSPGFPEKYPNNLECTYMIVAPVMAEILLEFGSFDLEPDSNLREGMLCRFDRLEIWDGFPGVGLHIGRFCGQVVPENIRSLTGILSLTLHTDTAIARDGFSANYSIIQKNLSENTHCNESLGMETGAIHSDQILTSSTYNLYWASERARLNYPENAWTPAEDSSKEWIQVDLGFLRQVSAIATQGAVSKETKKQYYIKSYKVDISSNGEDWITVKEKNKQKIFQGNSNPSEAVVRQFPQTVLTRYVRVRPLTWETGVALRFELYGCKFTDRPCSGMLGMVSGLISDNQVTASSTVDRYWAPEHARLLTSRSGWALQSASRPYNNEWLQIDLGVEKEVRSLIIQGAKQRENKVYMRKFKLAYSTNGSDWKMVSNPGSMKPKTFEGNSNYDTPEIRKFEPMLTRYIRVYPERASPAGLGLRMELLGCDIEVPTFPPTLDSDECDEDLGNCHSGTGDGFEFTDGNTALGTEEPTLPESPAFPDAIFPYEDNLNGFNCKFGSGVGKNFCNWRHDKATNFLWKVNSREGEADSRVPNLEKDHFIFTEIIGQEDGQVARLLSPPLLPVHHGHCLVFWYQIRGTHGSRLNVIQRKISDGFMNDVLWSLNGPQENRWQEGRVLLPQSPSMYQVGFEVMVRKGKQGEVAVHDVEVVSNRNANECMAPRNAFPGLVDGPTSVFPTVDDPEDPTNDSVGGSSGGPGNVLKTLDPILITIIAMSALGVILGAICGVVLYCACWHSALSDRNLSALENYNFELVDGVKLKKDKLSTQNSYSEA

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JW861885
EMBL· GenBank· DDBJ
AFO94402.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

Disclaimer

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