V9HVZ4 · V9HVZ4_HUMAN

  • Protein
    Glyceraldehyde-3-phosphate dehydrogenase
  • Gene
    HEL-S-162eP
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Evidence at transcript level
  • Annotation score
    4/5

Function

Catalytic activity

Pathway

Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 1/5.

Features

Showing features for binding site, active site, site.

TypeIDPosition(s)Description
Binding site13-14NAD+ (UniProtKB | ChEBI)
Binding site35NAD+ (UniProtKB | ChEBI)
Binding site80NAD+ (UniProtKB | ChEBI)
Binding site122NAD+ (UniProtKB | ChEBI)
Binding site151-153D-glyceraldehyde 3-phosphate (UniProtKB | ChEBI)
Active site152Nucleophile
Site179Activates thiol group during catalysis
Binding site182D-glyceraldehyde 3-phosphate (UniProtKB | ChEBI)
Binding site211-212D-glyceraldehyde 3-phosphate (UniProtKB | ChEBI)
Binding site234D-glyceraldehyde 3-phosphate (UniProtKB | ChEBI)
Binding site316NAD+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoskeleton
Cellular Componentcytosol
Cellular Componentintracellular membrane-bounded organelle
Cellular Componentnuclear membrane
Cellular Componentplasma membrane
Molecular Functionglyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
Molecular FunctionNAD binding
Molecular FunctionNADP binding
Molecular Functionpeptidyl-cysteine S-nitrosylase activity
Biological Processapoptotic process
Biological Processglucose metabolic process
Biological Processglycolytic process
Biological Processregulation of translation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Glyceraldehyde-3-phosphate dehydrogenase
  • EC number

Gene names

    • Name
      HEL-S-162eP

Organism names

  • Taxonomic identifier
  • Organism
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Hominidae > Homo

Accessions

  • Primary accession
    V9HVZ4

Organism-specific databases

Subcellular Location

Keywords

Disease & Variants

Organism-specific databases

PTM/Processing

Keywords

Expression

Gene expression databases

Interaction

Subunit

Homotetramer.

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain4-152Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding

Sequence similarities

Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    335
  • Mass (Da)
    36,053
  • Last updated
    2014-03-19 v1
  • Checksum
    C9C135E8AE3E8744
MGKVKVGVNGFGRIGRLVTRAAFNSGKVDIVAINDPFIDLNYMVYMFQYDSTHGKFHGTVKAENGKLVINGNPITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHLQGGAKRVIISAPSADAPMFVMGVNHEKYDNSLKIISNASCTTNCLAPLAKVIHDNFGIVEGLMTTVHAITATQKTVDGPSGKLWRDGRGALQNIIPASTGAAKAVGKVIPELNGKLTGMAFRVPTANVSVVDLTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEHQVVSSDFNSDTHSSTFDAGAGIALNDHFVKLISWYDNEFGYSNRVVDLMAHMASKE

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
EU668321
EMBL· GenBank· DDBJ
ACF94474.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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