V5V9F4 · V5V9F4_ACIBA

  • Protein
    Intermembrane phospholipid transport system permease protein MlaE
  • Gene
    mlaE
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Evidence at protein level
  • Annotation score
    2/5

Function

function

Part of the ABC transporter complex MlaFEDB, which is involved in a phospholipid transport pathway that maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. Probably responsible for the translocation of the substrate across the membrane.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular ComponentATP-binding cassette (ABC) transporter complex

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Intermembrane phospholipid transport system permease protein MlaE

Gene names

    • Name
      mlaE
    • Synonyms
      ttg2B
    • ORF names
      A7M90_14775
      , ABR2091_3298
      , APD33_11020
      , AUO97_04515
      , B9X95_19830
      , CV954_002080
      , CV955_0001970
      , EA706_02625
      , EA722_02115
      , EKS29_03575
      , EWP49_16265
      , F4T85_12835
      , FJU42_03310
      , FR761_17360
      , G3N53_10430
      , GSE42_18090
      , H0529_18335
      , IHV20_00460
      , JHZ39_001261
      , LV35_03499
      , MKP18_001965
      , OMP06_17050
      , P9867_02730
      , SAMEA104305340_01243

Organism names

  • Taxonomic identifier
  • Organism
  • Strains
    • ATCC 17978
    • ABBL072
    • R2091
    • AB2828
    • XH647
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Gammaproteobacteria > Moraxellales > Moraxellaceae > Acinetobacter > Acinetobacter calcoaceticus/baumannii complex

Accessions

  • Primary accession
    V5V9F4

Proteomes

Subcellular Location

Cell inner membrane
; Multi-pass membrane protein
Membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane20-43Helical
Transmembrane50-76Helical
Transmembrane145-165Helical
Transmembrane196-215Helical
Transmembrane236-255Helical

Keywords

Interaction

Subunit

The complex is composed of two ATP-binding proteins (MlaF), two transmembrane proteins (MlaE), two cytoplasmic solute-binding proteins (MlaB) and six periplasmic solute-binding proteins (MlaD).

Family & Domains

Sequence similarities

Belongs to the MlaE permease family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    258
  • Mass (Da)
    27,308
  • Last updated
    2014-02-19 v1
  • Checksum
    39C9F62AA17F3890
MNTIAWLGRLVIERIRGIGVAALMLLQIIFSLPSAGGFGRFVYQMHRVGVMSLLIITVSGLFIGLVLGLQGYSILVNVGSESMLGTMVSLTLLRELAPVVAALLFAGRAGSALTAEIGSMKQSEQLASMEMIGVDPLKQIVSPRLWAGIVSLPMLTVIFAAIGIVGGKLVGVDFLGVDEGSFWSGMQNNVQFGHDVVNGIIKSIVFALLCTWIAVFQGYACDPTPEGIATAMTRTVVYSSLCVLGFDFVLTAVMFGGI

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP018664
EMBL· GenBank· DDBJ
APP30115.1
EMBL· GenBank· DDBJ
Genomic DNA
LN997846
EMBL· GenBank· DDBJ
CUW36663.1
EMBL· GenBank· DDBJ
Genomic DNA
AAYLMQ010000011
EMBL· GenBank· DDBJ
EGY2376915.1
EMBL· GenBank· DDBJ
Genomic DNA
ABFEVW020000011
EMBL· GenBank· DDBJ
EKU3568569.1
EMBL· GenBank· DDBJ
Genomic DNA
ABFEVW030000011
EMBL· GenBank· DDBJ
EMN1071666.1
EMBL· GenBank· DDBJ
Genomic DNA
LLGC01000167
EMBL· GenBank· DDBJ
KQE04531.1
EMBL· GenBank· DDBJ
Genomic DNA
LRDT01000045
EMBL· GenBank· DDBJ
KZA12409.1
EMBL· GenBank· DDBJ
Genomic DNA
JACZEI010000001
EMBL· GenBank· DDBJ
MBE0328639.1
EMBL· GenBank· DDBJ
Genomic DNA
JARTMM010000005
EMBL· GenBank· DDBJ
MDK4880663.1
EMBL· GenBank· DDBJ
Genomic DNA
VYTH01000018
EMBL· GenBank· DDBJ
MQZ69263.1
EMBL· GenBank· DDBJ
Genomic DNA
WWCH01000001
EMBL· GenBank· DDBJ
MYM79826.1
EMBL· GenBank· DDBJ
Genomic DNA
JAAGTY010000010
EMBL· GenBank· DDBJ
NDW41489.1
EMBL· GenBank· DDBJ
Genomic DNA
LYKI01000006
EMBL· GenBank· DDBJ
OIG74412.1
EMBL· GenBank· DDBJ
Genomic DNA
NGEL01000189
EMBL· GenBank· DDBJ
OTM79211.1
EMBL· GenBank· DDBJ
Genomic DNA
PHJU02000006
EMBL· GenBank· DDBJ
PQL85224.1
EMBL· GenBank· DDBJ
Genomic DNA
PHJT03000005
EMBL· GenBank· DDBJ
PQL89004.1
EMBL· GenBank· DDBJ
Genomic DNA
CP042556
EMBL· GenBank· DDBJ
QFH46921.1
EMBL· GenBank· DDBJ
Genomic DNA
CP059300
EMBL· GenBank· DDBJ
QOJ59613.1
EMBL· GenBank· DDBJ
Genomic DNA
RFBY01000004
EMBL· GenBank· DDBJ
RSP80793.1
EMBL· GenBank· DDBJ
Genomic DNA
RFCO01000007
EMBL· GenBank· DDBJ
RSQ48885.1
EMBL· GenBank· DDBJ
Genomic DNA
RXYO01000022
EMBL· GenBank· DDBJ
RTY13201.1
EMBL· GenBank· DDBJ
Genomic DNA
SEUG01000009
EMBL· GenBank· DDBJ
RYL43063.1
EMBL· GenBank· DDBJ
Genomic DNA
UFNM01000004
EMBL· GenBank· DDBJ
SSU03698.1
EMBL· GenBank· DDBJ
Genomic DNA
VHGY01000008
EMBL· GenBank· DDBJ
TPU68219.1
EMBL· GenBank· DDBJ
Genomic DNA
CP110462
EMBL· GenBank· DDBJ
UZG61880.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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