V5V9F4 · V5V9F4_ACIBA
- ProteinIntermembrane phospholipid transport system permease protein MlaE
- GenemlaE
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids258 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score2/5
Function
function
Part of the ABC transporter complex MlaFEDB, which is involved in a phospholipid transport pathway that maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. Probably responsible for the translocation of the substrate across the membrane.
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | ATP-binding cassette (ABC) transporter complex |
Keywords
- Biological process
Names & Taxonomy
Protein names
- Recommended nameIntermembrane phospholipid transport system permease protein MlaE
Gene names
Organism names
- Organism
- Strains
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria > Moraxellales > Moraxellaceae > Acinetobacter > Acinetobacter calcoaceticus/baumannii complex
Accessions
- Primary accessionV5V9F4
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Cell inner membrane ; Multi-pass membrane protein
Membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 20-43 | Helical | ||||
Sequence: VAALMLLQIIFSLPSAGGFGRFVY | ||||||
Transmembrane | 50-76 | Helical | ||||
Sequence: VMSLLIITVSGLFIGLVLGLQGYSILV | ||||||
Transmembrane | 145-165 | Helical | ||||
Sequence: LWAGIVSLPMLTVIFAAIGIV | ||||||
Transmembrane | 196-215 | Helical | ||||
Sequence: VVNGIIKSIVFALLCTWIAV | ||||||
Transmembrane | 236-255 | Helical | ||||
Sequence: VVYSSLCVLGFDFVLTAVMF |
Keywords
- Cellular component
Interaction
Subunit
The complex is composed of two ATP-binding proteins (MlaF), two transmembrane proteins (MlaE), two cytoplasmic solute-binding proteins (MlaB) and six periplasmic solute-binding proteins (MlaD).
Structure
Sequence
- Sequence statusComplete
- Length258
- Mass (Da)27,308
- Last updated2014-02-19 v1
- Checksum39C9F62AA17F3890
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP018664 EMBL· GenBank· DDBJ | APP30115.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
LN997846 EMBL· GenBank· DDBJ | CUW36663.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AAYLMQ010000011 EMBL· GenBank· DDBJ | EGY2376915.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
ABFEVW020000011 EMBL· GenBank· DDBJ | EKU3568569.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
ABFEVW030000011 EMBL· GenBank· DDBJ | EMN1071666.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
LLGC01000167 EMBL· GenBank· DDBJ | KQE04531.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
LRDT01000045 EMBL· GenBank· DDBJ | KZA12409.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JACZEI010000001 EMBL· GenBank· DDBJ | MBE0328639.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JARTMM010000005 EMBL· GenBank· DDBJ | MDK4880663.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
VYTH01000018 EMBL· GenBank· DDBJ | MQZ69263.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
WWCH01000001 EMBL· GenBank· DDBJ | MYM79826.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
JAAGTY010000010 EMBL· GenBank· DDBJ | NDW41489.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
LYKI01000006 EMBL· GenBank· DDBJ | OIG74412.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
NGEL01000189 EMBL· GenBank· DDBJ | OTM79211.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
PHJU02000006 EMBL· GenBank· DDBJ | PQL85224.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
PHJT03000005 EMBL· GenBank· DDBJ | PQL89004.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
CP042556 EMBL· GenBank· DDBJ | QFH46921.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
CP059300 EMBL· GenBank· DDBJ | QOJ59613.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
RFBY01000004 EMBL· GenBank· DDBJ | RSP80793.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
RFCO01000007 EMBL· GenBank· DDBJ | RSQ48885.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
RXYO01000022 EMBL· GenBank· DDBJ | RTY13201.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
SEUG01000009 EMBL· GenBank· DDBJ | RYL43063.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
UFNM01000004 EMBL· GenBank· DDBJ | SSU03698.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
VHGY01000008 EMBL· GenBank· DDBJ | TPU68219.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
CP110462 EMBL· GenBank· DDBJ | UZG61880.1 EMBL· GenBank· DDBJ | Genomic DNA |