V5N6T4 · V5N6T4_GOBRA

Function

function

Catalyzes the degradation of hydrogen peroxide (H2O2) generated by peroxisomal oxidases to water and oxygen, thereby protecting cells from the toxic effects of hydrogen peroxide.

Catalytic activity

Cofactor

Protein has several cofactor binding sites:
NADP+ (UniProtKB | Rhea| CHEBI:58349 )

heme (UniProtKB | Rhea| CHEBI:30413 )

Features

Showing features for active site, binding site.

152550100150200250300350400450500
TypeIDPosition(s)Description
Active site74
Active site147
Binding site357Fe (UniProtKB | ChEBI) of heme (UniProtKB | ChEBI); axial binding residue

GO annotations

AspectTerm
Cellular Componentmitochondrion
Cellular Componentperoxisomal matrix
Molecular Functioncatalase activity
Molecular Functionheme binding
Molecular Functionmetal ion binding
Biological Processhydrogen peroxide catabolic process
Biological Processresponse to hydrogen peroxide

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Catalase
  • EC number

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Ostariophysi > Cypriniformes > Gobionidae > Sarcocheilichthyinae > Gobiocypris

Accessions

  • Primary accession
    V5N6T4

Subcellular Location

Keywords

Family & Domains

Features

Showing features for compositional bias, region, domain.

TypeIDPosition(s)Description
Compositional bias1-19Basic and acidic residues
Region1-31Disordered
Domain27-412Catalase core

Sequence similarities

Belongs to the catalase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    525
  • Mass (Da)
    59,461
  • Last updated
    2014-02-19 v1
  • Checksum
    6157BFF078AF2A09
MADRDKATDQMKLWKEGRGSQRPDVLTTGAGVPVGDKLNSMTAGARGPLLVQDVVFTDEMAHFDRERIPERVVHAKGAGAFGYFEVTHDITRYCKAKVFEHVGKTTPIAIRFSTVAGESGSADTVRDPRGFAVKFYTDEGNWDLTGNNTPIFFIRDALLFPSFIHSQKRNPQTHLKDPDMVWDFWGLRPEALHQVSFLFSDRGIPDGYRHMNGYGSHTFKLVNAQGQPVYCKFHYKTDQGIKNLTVEEADRLSSTDPDYSIRDLYNAISNGNFPSWTFYIQVMTFEQAENWKWNPFDLTKVWSHKDFPLIPVGRLVLNRNPVNYFSEVEQLAFDPSNMPPGIEPSPDKMLQGRLFSYPDTHRHRLGANYLQLPVNCPYRTRVANYQRDGPMCMYDNQGGAPNYFPNSFSAPDTQPCFMESKCQVSPDVGRYNSADDDNVTQVRTFFTEVLNEAERERLCQNMAGHMKGAQLFIQKRVVQNLMAIHPDYGTRVQTVLDKLNAEGKKNTIHVYSRGGASAVAAASKM

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias1-19Basic and acidic residues

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
KF515698
EMBL· GenBank· DDBJ
AHA82626.1
EMBL· GenBank· DDBJ
mRNA

Similar Proteins

Disclaimer

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