V5KAK3 · V5KAK3_9BRAN
- ProteinPhosphotransferase
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids458 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score3/5
Function
Catalytic activity
- D-fructose + ATP = D-fructose 6-phosphate + ADP + H+This reaction proceeds in the forward direction.
Pathway
Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 1/4.
Carbohydrate metabolism; hexose metabolism.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Cellular Component | mitochondrion | |
Molecular Function | ATP binding | |
Molecular Function | D-glucose binding | |
Molecular Function | fructokinase activity | |
Molecular Function | glucokinase activity | |
Biological Process | glucose metabolic process | |
Biological Process | glycolytic process | |
Biological Process | intracellular glucose homeostasis |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namePhosphotransferase
- EC number
Organism names
- Taxonomic lineageEukaryota > Metazoa > Chordata > Cephalochordata > Leptocardii > Amphioxiformes > Branchiostomatidae > Branchiostoma
Accessions
- Primary accessionV5KAK3
Subcellular Location
UniProt Annotation
GO Annotation
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 16-210 | Hexokinase N-terminal | ||||
Sequence: IDLILRPFRYDNDTLNDIMGRLHKEMEKGLKKETNPDATVKMLATYVRAVPDGTESGDFLSLDLGGSNFRVLHVHIEKGAKDVRLQSDSYAIPENIMTGPGEQLFDYIADCMAKFLEKIGMKERKMALGFTFSFPCKQRGLDCASLIKWTKGFSAAGVEGEDVVRLLRDAIKRRGDFDTDVVAVVNDTVGTMMAC | ||||||
Domain | 219-450 | Hexokinase C-terminal | ||||
Sequence: IGLIVGTGSNACYMEKLDNVEIWEGERGEPNQVVVNMEWGAFGEDGALDDLRTPYDREIDEHSINKGQQIYEKMISGMYMGELVRLVLLEMTKQMLVFGGRTSTELETRGTFQTKYVSEIEEEPIGDMGPTMKILHSLGLKHATETDCGTVREVCRAVSTRAAHLVSAGISAIVNKMGRERVAVGVDGSVYKYHPHFKELMTQTIDKLTHCDVKLMLSEDGSGKGAALVTAV |
Sequence similarities
Belongs to the hexokinase family.
Family and domain databases
Sequence
- Sequence statusComplete
- Length458
- Mass (Da)50,512
- Last updated2014-02-19 v1
- Checksum427B72753841E24E