V4YKR3 · V4YKR3_9PROT
- ProteinATP-dependent DNA helicase Rep
- Generep
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids685 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction.
Catalytic activity
- ATP + H2O = ADP + phosphate + H+
Features
Showing features for binding site.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Molecular Function | 3'-5' DNA helicase activity | |
Molecular Function | ATP binding | |
Molecular Function | ATP hydrolysis activity | |
Molecular Function | isomerase activity | |
Molecular Function | single-stranded DNA binding | |
Biological Process | DNA unwinding involved in DNA replication | |
Biological Process | recombinational repair |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameATP-dependent DNA helicase Rep
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Betaproteobacteria
Accessions
- Primary accessionV4YKR3
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Interaction
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 3-277 | UvrD-like helicase ATP-binding | ||||
Sequence: SGLNPAQLEAVHHVSGPSLVLAGAGSGKTRVITHKIAYLIEGGLSPSRIAAITFTNKAAAEMRERAKQLAGKVAGQVLICTFHALGVRMLRQQGSYVGLKEQFSILDSDDVSRILKDCGGSTDLATAKQWQWTISAWKNAGLNAAQALAGAADEDQRVAATIMGRYEERLAAYQSVDFDDLISLPLKLLKEHEVVRQHWQQQLGHVLVDEYQDTNATQYDLLKLLVGDGARLTAVGDDDQSIYGWRGATLDNLKKLPLDFPQLKVIMLEQNYRST | ||||||
Domain | 278-571 | UvrD-like helicase C-terminal | ||||
Sequence: TAILDAANNVIGPNPKLFPKTLWSDLGQGEPVRVVACDVEDHEAERAVARIQSLRSSSQHKAYRDFAILYRANHQARVFEKALRKVQIPYKVSGGQSFFDRAEIKDLCAWLRLLVNNDDDPAFLRAITTPKRGIGHTSLSQLGQFATSHKLSLFEALFANSLAGSVPARAVAGLHEFGRYINDLEFRARQTLGKDDAKAFLLEWLKDMNYEQHLLEGEDNPKAAANRWSNVLDFIDWMSQRCGGEMDDTAGATLATETKTLLEVVQTIALLSTISEREQDQDVVTLSTLHASKG |
Sequence similarities
Belongs to the helicase family. UvrD subfamily.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length685
- Mass (Da)75,819
- Last updated2014-01-22 v1
- Checksum523DBBEE83CA264D
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AYMW01000001 EMBL· GenBank· DDBJ | ESS15443.1 EMBL· GenBank· DDBJ | Genomic DNA |