V4YKR3 · V4YKR3_9PROT

Function

function

Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site24-31ATP (UniProtKB | ChEBI)
Binding site275ATP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular Function3'-5' DNA helicase activity
Molecular FunctionATP binding
Molecular FunctionATP hydrolysis activity
Molecular Functionisomerase activity
Molecular Functionsingle-stranded DNA binding
Biological ProcessDNA unwinding involved in DNA replication
Biological Processrecombinational repair

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    ATP-dependent DNA helicase Rep
  • EC number
  • Alternative names
    • DNA 3'-5' helicase Rep

Gene names

    • Name
      rep
    • ORF names
      MOLA814_01020

Organism names

Accessions

  • Primary accession
    V4YKR3

Proteomes

Subcellular Location

Interaction

Subunit

Homodimer.

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain3-277UvrD-like helicase ATP-binding
Domain278-571UvrD-like helicase C-terminal

Sequence similarities

Belongs to the helicase family. UvrD subfamily.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    685
  • Mass (Da)
    75,819
  • Last updated
    2014-01-22 v1
  • Checksum
    523DBBEE83CA264D
MSSGLNPAQLEAVHHVSGPSLVLAGAGSGKTRVITHKIAYLIEGGLSPSRIAAITFTNKAAAEMRERAKQLAGKVAGQVLICTFHALGVRMLRQQGSYVGLKEQFSILDSDDVSRILKDCGGSTDLATAKQWQWTISAWKNAGLNAAQALAGAADEDQRVAATIMGRYEERLAAYQSVDFDDLISLPLKLLKEHEVVRQHWQQQLGHVLVDEYQDTNATQYDLLKLLVGDGARLTAVGDDDQSIYGWRGATLDNLKKLPLDFPQLKVIMLEQNYRSTTAILDAANNVIGPNPKLFPKTLWSDLGQGEPVRVVACDVEDHEAERAVARIQSLRSSSQHKAYRDFAILYRANHQARVFEKALRKVQIPYKVSGGQSFFDRAEIKDLCAWLRLLVNNDDDPAFLRAITTPKRGIGHTSLSQLGQFATSHKLSLFEALFANSLAGSVPARAVAGLHEFGRYINDLEFRARQTLGKDDAKAFLLEWLKDMNYEQHLLEGEDNPKAAANRWSNVLDFIDWMSQRCGGEMDDTAGATLATETKTLLEVVQTIALLSTISEREQDQDVVTLSTLHASKGLEWPHVILAGVNEGLLPFKTDDDSLTAEALSMRLQEERRLMYVGITRAQRTLAVSWLLRRKKGRDTVAGKPSRFIAEMALDKATVREDPREKLRALRAEFAAKAQLSAEAAKQL

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AYMW01000001
EMBL· GenBank· DDBJ
ESS15443.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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