V4MA29 · V4MA29_EUTSA

Function

function

Cleaves the gamma-glutamyl peptide bond of glutathione and glutathione conjugates.

Catalytic activity

Pathway

Sulfur metabolism; glutathione metabolism.

Features

Showing features for binding site, active site.

Type
IDPosition(s)Description
Binding site99L-glutamate (UniProtKB | ChEBI)
Active site368Nucleophile
Binding site386-388L-glutamate (UniProtKB | ChEBI)
Binding site410L-glutamate (UniProtKB | ChEBI)
Binding site440-441L-glutamate (UniProtKB | ChEBI)
Binding site462L-glutamate (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentplasma membrane
Molecular Functionacyltransferase activity
Molecular Functionglutathione hydrolase activity
Biological Processglutathione catabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Glutathione hydrolase
  • EC number
  • Alternative names
    • Gamma-glutamyltransferase
    • Gamma-glutamyltranspeptidase

Gene names

    • ORF names
      EUTSA_v10024781mg

Organism names

Accessions

  • Primary accession
    V4MA29

Proteomes

Genome annotation databases

Subcellular Location

PTM/Processing

Features

Showing features for signal, chain.

Type
IDPosition(s)Description
Signal1-22
ChainPRO_500472464223-572Glutathione hydrolase

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for region.

TypeIDPosition(s)Description
Region552-572Disordered

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    572
  • Mass (Da)
    61,269
  • Last updated
    2014-01-22 v1
  • MD5 Checksum
    D3833A2953932FF008A15C3CD541BA98
MSLVRTATIALILIAFLQNAAAQKRPQSIVKYRGAVATDDGRCSEIGMSVLRQGGNAIDASVAAALCLGVVSPASSGIGGGAFTVVKIAGGKAIAYDSRETAPLHASEDMYGGNLDLKKKGALSVGVPGEVAGLFIAWKQHGKLPWKRLVRPAEKLAKGFRISKYLYMQMNTTRSDILADKGLSALFVSNGELKKPGTIICNPKLALTLRQIAEYGPKAFYNGTVGVNLARDILKSGGIITLKDLQSYRVKVKEPLSTDILGYRLLGMPPPSSGGAAMMLVLNIISQYGIPTGVSGSLGVHRLIEALKHAFAIRMNLADPDFVNVTKVVSDMLSSKFAKDLKRKINDEKTFDPKYYGGMWNQIDDHGTSHLSIIDHERNAVSMTSTINGYFGALMLSPSTGIVLNNEMDDFSIPMKTSGNINVPPPAPANFIRPGKRPLSSMTPTIVLKDGKVKAAVGASGGANIIAGTTEVFLNHFFLKMDPLSSVLAPRIYHQLIPNRVTFENWTTVFSDHFEVPKETRVVLEKKGHVLTPIAGGTIAQFIVEESGENSGGRSELVAVSDPRKGGFPSGY

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
KI517384
EMBL· GenBank· DDBJ
ESQ53209.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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