V4MA29 · V4MA29_EUTSA
- ProteinGlutathione hydrolase
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids572 (go to sequence)
- Protein existencePredicted
- Annotation score3/5
Function
function
Cleaves the gamma-glutamyl peptide bond of glutathione and glutathione conjugates.
Catalytic activity
- an N-terminal (5-L-glutamyl)-[peptide] + an alpha-amino acid = 5-L-glutamyl amino acid + an N-terminal L-alpha-aminoacyl-[peptide]
Pathway
Sulfur metabolism; glutathione metabolism.
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 99 | L-glutamate (UniProtKB | ChEBI) | |||
Active site | 368 | Nucleophile | |||
Binding site | 386-388 | L-glutamate (UniProtKB | ChEBI) | |||
Binding site | 410 | L-glutamate (UniProtKB | ChEBI) | |||
Binding site | 440-441 | L-glutamate (UniProtKB | ChEBI) | |||
Binding site | 462 | L-glutamate (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | plasma membrane | |
Molecular Function | acyltransferase activity | |
Molecular Function | glutathione hydrolase activity | |
Biological Process | glutathione catabolic process |
Keywords
- Molecular function
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameGlutathione hydrolase
- EC number
- Alternative names
Gene names
Organism names
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Eutremeae > Eutrema
Accessions
- Primary accessionV4MA29
Proteomes
Genome annotation databases
Subcellular Location
UniProt Annotation
GO Annotation
PTM/Processing
Features
Showing features for signal, chain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Signal | 1-22 | ||||
Chain | PRO_5004724642 | 23-572 | Glutathione hydrolase | ||
Interaction
Protein-protein interaction databases
Structure
Sequence
- Sequence statusComplete
- Length572
- Mass (Da)61,269
- Last updated2014-01-22 v1
- MD5 ChecksumD3833A2953932FF008A15C3CD541BA98
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
KI517384 EMBL· GenBank· DDBJ | ESQ53209.1 EMBL· GenBank· DDBJ | Genomic DNA |