V1H5S4 · V1H5S4_SALER
- ProteindTTP/UTP pyrophosphatase
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids197 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
Catalytic activity
- UTP + H2O = UMP + diphosphate + H+
Cofactor
Features
Showing features for site, active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Site | 12 | Important for substrate specificity | |||
Active site | 70 | Proton acceptor | |||
Site | 71 | Important for substrate specificity | |||
Site | 153 | Important for substrate specificity | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | dTTP diphosphatase activity | |
Molecular Function | UTP diphosphatase activity | |
Biological Process | nucleotide metabolic process |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namedTTP/UTP pyrophosphatase
- EC number
- Short namesdTTPase/UTPase
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria > Enterobacterales > Enterobacteriaceae > Salmonella
Accessions
- Primary accessionV1H5S4
Proteomes
Subcellular Location
Interaction
Protein-protein interaction databases
Structure
Sequence
- Sequence statusComplete
- Length197
- Mass (Da)21,443
- Last updated2014-01-22 v1
- MD5 ChecksumB72F8BDF646B26F7650984AAE51F6F91
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AOXI01000012 EMBL· GenBank· DDBJ | ESE86707.1 EMBL· GenBank· DDBJ | Genomic DNA |