V1H5S4 · V1H5S4_SALER

Function

function

Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

a divalent metal cation (UniProtKB | Rhea| CHEBI:60240 )

Features

Showing features for site, active site.

Type
IDPosition(s)Description
Site12Important for substrate specificity
Active site70Proton acceptor
Site71Important for substrate specificity
Site153Important for substrate specificity

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctiondTTP diphosphatase activity
Molecular FunctionUTP diphosphatase activity
Biological Processnucleotide metabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    dTTP/UTP pyrophosphatase
  • EC number
  • Short names
    dTTPase/UTPase
  • Alternative names
    • Nucleoside triphosphate pyrophosphatase
    • Nucleotide pyrophosphatase
      (Nucleotide PPase
      )

Gene names

    • ORF names
      SEI61121_04859

Organism names

Accessions

  • Primary accession
    V1H5S4

Proteomes

Subcellular Location

Keywords

Interaction

Protein-protein interaction databases

Family & Domains

Sequence similarities

Belongs to the Maf family. YhdE subfamily.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    197
  • Mass (Da)
    21,443
  • Last updated
    2014-01-22 v1
  • MD5 Checksum
    B72F8BDF646B26F7650984AAE51F6F91
MTTLYLASGSPRRQELLTQLGFSFEQVVPGIEEQRRAQESAPQYVVRLAREKAQAGVALVPRDLPVLGADTIVVLNGKVLEKPRDAAHAAEMLRLLSGNTHQVMTAVALADSQQMLDCLVVTEVTFRTLSAQDIADYVASGEPLDKAGAYGIQGRGGCFVRKINGSYHAVVGLPLVETYELLSHFNALRDKRDKHDG

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AOXI01000012
EMBL· GenBank· DDBJ
ESE86707.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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