U7GRY4 · U7GRY4_9GAMM

  • Protein
    tRNA (cytidine(34)-2'-O)-methyltransferase
  • Gene
    trmL
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site78S-adenosyl-L-methionine (UniProtKB | ChEBI)
Binding site100S-adenosyl-L-methionine (UniProtKB | ChEBI)
Binding site122S-adenosyl-L-methionine (UniProtKB | ChEBI)
Binding site130S-adenosyl-L-methionine (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctionRNA binding
Molecular FunctiontRNA (5-carboxymethylaminomethyluridine(34)-2'-O)-methyltransferase activity
Molecular FunctiontRNA (cytidine(34)-2'-O)-methyltransferase activity
Biological Processwobble position cytosine ribose methylation
Biological Processwobble position uridine ribose methylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    tRNA (cytidine(34)-2'-O)-methyltransferase
  • EC number
  • Alternative names
    • tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmL

Gene names

    • Name
      trmL
    • ORF names
      Q673_09785

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • EN3
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Gammaproteobacteria > Pseudomonadales > Marinobacteraceae > Marinobacter

Accessions

  • Primary accession
    U7GRY4

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

Homodimer.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain2-142tRNA/rRNA methyltransferase SpoU type

Sequence similarities

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    154
  • Mass (Da)
    17,444
  • Last updated
    2014-01-22 v1
  • MD5 Checksum
    2FCAF8DFADE36879EBA220FC613B2E2C
MLHVVLYEPEIPPNTGNIIRLCANTGCQLHLIQPLGFSLEDKQMRRAGLDYSEYATVKIHADYASFLATEQPSRLFGLTTKGSRHYHEVVFRDGDYLMFGPETRGLPEDVRNGLPAEHRLRVPMRPESRSLNLSNTAALVVYEAWRQLGFEGSI

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AXCC01000096
EMBL· GenBank· DDBJ
ERS00568.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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