U6BQ50 · U6BQ50_CLABA
- ProteinGlutathione peroxidase
- GeneGPx1
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids190 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score2/5
Function
Catalytic activity
- (12S)-hydroperoxy-(5Z,8Z,10E,14Z)-eicosatetraenoate + 2 glutathione = (12S)-hydroxy-(5Z,8Z,10E,14Z)-eicosatetraenoate + glutathione disulfide + H2OThis reaction proceeds in the forward direction.
Features
Showing features for active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Active site | 39 | ||||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Cellular Component | mitochondrion | |
Molecular Function | glutathione peroxidase activity | |
Biological Process | glutathione metabolic process | |
Biological Process | hydrogen peroxide catabolic process | |
Biological Process | response to hydrogen peroxide | |
Biological Process | response to selenium ion |
Keywords
- Molecular function
- Ligand
Names & Taxonomy
Protein names
- Recommended nameGlutathione peroxidase
Gene names
Organism names
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Ostariophysi > Siluriformes > Clariidae > Clarias
Accessions
- Primary accessionU6BQ50
Subcellular Location
UniProt Annotation
GO Annotation
Interaction
Subunit
Homotetramer. Interacts with MIEN1.
Structure
Sequence
- Sequence statusComplete
- Length190
- Mass (Da)21,361
- Last updated2015-09-16 v2
- MD5 Checksum22209155B0B2F291592DDE2DC937740F
Features
Showing features for non-standard residue.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Non-standard residue | 39 | Selenocysteine | |||
Keywords
- Coding sequence diversity
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
KF414736 EMBL· GenBank· DDBJ | AHA36867.2 EMBL· GenBank· DDBJ | mRNA |