U5TPM4 · U5TPM4_COWPX

  • Protein
    Protein OPG166
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    2/5

Function

function

Promotes, when overexpressed, the influx of extracellular Ca2+, leading to membrane permeability and host cell necrosis.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentextracellular exosome
Cellular Componenthost cell membrane
Cellular Componentplasma membrane
Molecular Functionthrombospondin receptor activity
Biological Processpositive regulation of cell-cell adhesion
Biological Processpositive regulation of inflammatory response
Biological Processpositive regulation of phagocytosis

Names & Taxonomy

Protein names

  • Recommended name
    Protein OPG166

Gene names

    • ORF names
      CPXV175

Organism names

Accessions

  • Primary accession
    U5TPM4

Proteomes

Subcellular Location

Host membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane125-144Helical
Transmembrane156-177Helical
Transmembrane183-201Helical
Transmembrane213-235Helical
Transmembrane247-269Helical

Keywords

PTM/Processing

Keywords

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain4-122CD47 immunoglobulin-like
Domain126-269CD47-like transmembrane

Sequence similarities

Belongs to the orthopoxvirus OPG166 protein family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    277
  • Mass (Da)
    31,633
  • Last updated
    2014-01-22 v1
  • Checksum
    CABF27F7B703E6DF
MLRVRILLIYLCTFVVITSTKTIEYTACNYTIIIPCTIDNPTKYIRWKLDNHDILTYNKTSKTTILSKWHTSAKLHSLSDNDVSLIIEYKDILPGTYTCEDNTGIKSTVKLVQRHTNWFNDHHTMLMFIFTGITLFLLFLEIAYTSISVVFSTNLGILQVFGCIIAMIELCGAFLFYPSMFTLRHIIGLLMMTLPSIFLIITKVFSFWLLCKLSCAVHLIIYYQLAGYILTVLGLGLSLKECVDGTLLLSGLGTIMVSEHFSLLFLVCFPSTQRDYY

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
KC813501
EMBL· GenBank· DDBJ
AGY99259.1
EMBL· GenBank· DDBJ
Genomic DNA
KC813503
EMBL· GenBank· DDBJ
AGY99677.1
EMBL· GenBank· DDBJ
Genomic DNA
KC813505
EMBL· GenBank· DDBJ
AGZ00107.1
EMBL· GenBank· DDBJ
Genomic DNA
KC813508
EMBL· GenBank· DDBJ
AGZ00740.1
EMBL· GenBank· DDBJ
Genomic DNA
KC813510
EMBL· GenBank· DDBJ
AGZ01160.1
EMBL· GenBank· DDBJ
Genomic DNA
KC813512
EMBL· GenBank· DDBJ
AGZ01584.1
EMBL· GenBank· DDBJ
Genomic DNA
MK035746
EMBL· GenBank· DDBJ
AZY89032.1
EMBL· GenBank· DDBJ
Genomic DNA
MK035747
EMBL· GenBank· DDBJ
AZY89213.1
EMBL· GenBank· DDBJ
Genomic DNA
MK035748
EMBL· GenBank· DDBJ
AZY89399.1
EMBL· GenBank· DDBJ
Genomic DNA
MK035749
EMBL· GenBank· DDBJ
AZY89581.1
EMBL· GenBank· DDBJ
Genomic DNA
MK035750
EMBL· GenBank· DDBJ
AZY89757.1
EMBL· GenBank· DDBJ
Genomic DNA
MK035753
EMBL· GenBank· DDBJ
AZY90307.1
EMBL· GenBank· DDBJ
Genomic DNA
MK035757
EMBL· GenBank· DDBJ
AZY91054.1
EMBL· GenBank· DDBJ
Genomic DNA
MK035759
EMBL· GenBank· DDBJ
AZY91429.1
EMBL· GenBank· DDBJ
Genomic DNA
LN864565
EMBL· GenBank· DDBJ
CRL86667.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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