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U5Q9W7 · U5Q9W7_9GOBI

Function

function

Photoreceptor required for image-forming vision at low light intensity. While most salt water fish species use retinal as chromophore, most freshwater fish use 3-dehydroretinal, or a mixture of retinal and 3-dehydroretinal. Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change that activates signaling via G-proteins. Subsequent receptor phosphorylation mediates displacement of the bound G-protein alpha subunit by arrestin and terminates signaling.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Features

Showing features for site, binding site.

128120406080100120140160180200220240260280
Type
IDPosition(s)Description
Site86Plays an important role in the conformation switch to the active conformation
Binding site174Zn2+ (UniProtKB | ChEBI)
Binding site252Zn2+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentmembrane
Cellular Componentphotoreceptor outer segment
Molecular FunctionG protein-coupled photoreceptor activity
Molecular Functionmetal ion binding
Biological Processcellular response to light stimulus
Biological Processphototransduction
Biological Processvisual perception

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Rhodopsin

Gene names

    • Name
      Rh

Organism names

  • Taxonomic identifier
  • Organism
  • Strains
    • SzJa22
    • SzJa26
    • SzNC03
    • SzNC20
    • SzNC35
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Neoteleostei > Acanthomorphata > Gobiaria > Gobiiformes > Gobioidei > Gobiidae > Sicydiinae > Sicyopus

Accessions

  • Primary accession
    U5Q9W7

Subcellular Location

Membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane12-36Helical
Transmembrane48-68Helical
Transmembrane88-106Helical
Transmembrane126-146Helical
Transmembrane176-196Helical
Transmembrane227-249Helical

Keywords

PTM/Processing

Features

Showing features for disulfide bond, modified residue.

Type
IDPosition(s)Description
Disulfide bond83↔160
Modified residue269N6-(retinylidene)lysine

Post-translational modification

Contains one covalently linked retinal chromophore.

Keywords

Structure

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain27-279G-protein coupled receptors family 1 profile

Sequence similarities

Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.

Keywords

Family and domain databases

Protein family/group databases

Sequence

  • Sequence status
    Fragment
  • Length
    281
  • Mass (Da)
    31,683
  • Last updated
    2014-01-22 v1
  • MD5 Checksum
    D0E87DF20885DDD90EF3AC70FF3F5488
QYYLVNPAAYAALGAYMFFLILAGFPINFLTLYVTIEHKKLRTPLNYILLNLAVADLFMVFGGFTTTMYTSMHGYFVLGRLGCNLEGFFATLGGEIGLWSLVVLAIERWIVVCKPISNFRFGENHAIMGVALTWIMACSCAVPPLVGWSRYIPEGMQCSCGVDYYTRAEGFNNESFVIYMFIVHFSIPFTVIFFCYGRLLCAVKEAAAAQQESETTQRAEREVTRMVVIMVIAFLVSWLPYASVAWYIFTHQGSEFGPLFMTLPAFFAKSSAIYNPLIYIC

Features

Showing features for non-terminal residue.

TypeIDPosition(s)Description
Non-terminal residue1
Non-terminal residue281

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
KC407233
EMBL· GenBank· DDBJ
AGY55530.1
EMBL· GenBank· DDBJ
Genomic DNA
KC407234
EMBL· GenBank· DDBJ
AGY55531.1
EMBL· GenBank· DDBJ
Genomic DNA
KC407235
EMBL· GenBank· DDBJ
AGY55532.1
EMBL· GenBank· DDBJ
Genomic DNA
KC407236
EMBL· GenBank· DDBJ
AGY55533.1
EMBL· GenBank· DDBJ
Genomic DNA
KC407238
EMBL· GenBank· DDBJ
AGY55535.1
EMBL· GenBank· DDBJ
Genomic DNA
KC407239
EMBL· GenBank· DDBJ
AGY55536.1
EMBL· GenBank· DDBJ
Genomic DNA
KC407240
EMBL· GenBank· DDBJ
AGY55537.1
EMBL· GenBank· DDBJ
Genomic DNA
KC407241
EMBL· GenBank· DDBJ
AGY55538.1
EMBL· GenBank· DDBJ
Genomic DNA
KC407242
EMBL· GenBank· DDBJ
AGY55539.1
EMBL· GenBank· DDBJ
Genomic DNA
KC407243
EMBL· GenBank· DDBJ
AGY55540.1
EMBL· GenBank· DDBJ
Genomic DNA
KC407244
EMBL· GenBank· DDBJ
AGY55541.1
EMBL· GenBank· DDBJ
Genomic DNA
KC407245
EMBL· GenBank· DDBJ
AGY55542.1
EMBL· GenBank· DDBJ
Genomic DNA
KC407246
EMBL· GenBank· DDBJ
AGY55543.1
EMBL· GenBank· DDBJ
Genomic DNA
KC407247
EMBL· GenBank· DDBJ
AGY55544.1
EMBL· GenBank· DDBJ
Genomic DNA
KC407248
EMBL· GenBank· DDBJ
AGY55545.1
EMBL· GenBank· DDBJ
Genomic DNA
KC407249
EMBL· GenBank· DDBJ
AGY55546.1
EMBL· GenBank· DDBJ
Genomic DNA
KC407250
EMBL· GenBank· DDBJ
AGY55547.1
EMBL· GenBank· DDBJ
Genomic DNA
KC407251
EMBL· GenBank· DDBJ
AGY55548.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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