U5KCA6 · U5KCA6_AMBHE
- ProteinVitellogenin receptor
- GeneVgR
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids1801 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score2/5
Function
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | apical plasma membrane | |
Cellular Component | receptor complex | |
Molecular Function | calcium ion binding | |
Molecular Function | hormone binding | |
Biological Process | receptor-mediated endocytosis |
Keywords
- Molecular function
- Biological process
Names & Taxonomy
Protein names
- Submitted names
Gene names
Organism names
- Taxonomic lineageEukaryota > Metazoa > Ecdysozoa > Arthropoda > Chelicerata > Arachnida > Acari > Parasitiformes > Ixodida > Ixodoidea > Ixodidae > Amblyomminae > Amblyomma
Accessions
- Primary accessionU5KCA6
Subcellular Location
UniProt Annotation
GO Annotation
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 1671-1692 | Helical | ||||
Sequence: WLAPILIALMCVALLVLGYVLY |
Keywords
- Cellular component
PTM/Processing
Features
Showing features for signal, chain, disulfide bond.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Signal | 1-22 | |||||
Sequence: MEAVRRVLLAVFLLQLALEASS | ||||||
Chain | PRO_5004662093 | 23-1801 | ||||
Sequence: ECPQGWFDCQNGRCIAMFWRCDGQNDCGNHKDETGCSAPRPVCPVGKFACHDHSYCVPEIWLCDGEGDCHDSSDELDCQAKNCTGYRCHNNECIPNHWRCDQTEDCADASDELDCTATVGAGSTTTVSPRCNIDQGHFPCLDGQCLLPGKVCDGKKDCTDGADEGTFCKINECSQKKCSQGCFVATNGSTCYCNPGFRLMADHVSCADIDECAEQPHICSHGCTNSPGSYKCSCLDGYQLTDNSFCKARDQEPLLLFSATNEIRGLWLRSNRYFEVHPAEAQAVGVEFDSDELRVFWTDVSTAKSSVYSCRLDGSGFKTLFSAERTLLEDLSLDWVTNNLYITDSLVKRILVCSTDGVSCGAVVTTELDAPRAIIVDPANRFMYWTDWGVKPAVVRSNMDGSNIQRLVSTNLGWPNGLALDHATNSLYWCDAKLSKLEYLDLATMKRTVVLDESLFHPFALSVFEDTVYWSDWASYSLDTSNKLTGKQHHRLLRENGRHIMGVHVYHPVLRLQGISNPCWDHPCDHICVLSGDSYMCLCRLGYKLTANKHSCTVTKDLSFAIVAEEDSLYKIDLRTVGAPVAIKMPLSDAGVIAALAFDWSNQTLYFSDNRREVISSFSVNSFEQRTIHDHIGSVFGMDFDMTHGLLYWVDADKYTLEVCRANGSGHAIVRDDLRRPVGLALYPFAGVLFVLSAGDKPAITSYTMDGQNPKPVPLASLLLPVSIAVDLVAKKLVWADAIRRTIESLDLVTVFSSTPFIVQQVKSHICSVSAAHNEIHWTSRDNSSLEYIDLSAVPHVRRHVPLGTVRNGTYSRRVFVASQVPDFEPGPCGRNNGGCSHTCLPVRTTDRACFCPPGMALNSDNTTCRVENGTCRPHELPCAGGCIAAAYWCDGHKDCADNADEAACVETCPSKDFTCQNGKCIDMDWRCDGYDDCDDQSDEANCPYHTCASHQFTCKSGACLPLYWRCDGGRDCPDGDDELDCRTFRCPNGYDRCSNGQCIPLDWTCDGHADCSDSSDETNCTETTSCLEGDFHCSNGQCVDKRLRCDHDSDCEDDSDESGCDYAPANKSQCVRGMVGCGDGQCVYTHDVCDGYADCHNGWDEHNCSAPICQSAEFFCTGTKRCILQSWLCDGDDDCGDAMDELLARCRPTTLPPPTDAPCWSDQFQCGSHECIAWSSVCDGRTDCADFSDEGSHCEHHCATANGGCAHVCRESPSGPQCSCRPGYRLNNDRKSCDDIDECLSPGHCSHYCQNSKGSFKCTCADGYALGADRRYCKVQYGEAFLLYMLPNQIRSFSMHGHAQHLLAEDTLADMHGMDYRIGDKSIFWTEMEEGIINVVTLGNGKHFTLLEDIHRPFHIAVDWVAGNIYFTDGWVHIQACEPTFKHCTDVVDTAYSHVNTFALAANDGLMFWGVWHEIVAKNYGVIERANMDGSDRRVLLSDKILWPCSITVDAVHLRIYWSDANKNVIESATYQGADRKLVRGTGLSSPFSIALFEDWLYWSDWGSDSLMACNKYTGGNVALVHHGMTKASVLKVLHAVHQPSGINRCARNQCGHICLLKPNSSTCACGHGFSLAKDSRNCVESDDRYYNLTSADVLGQLCNPVCLNGGHCISEKSSYYCRCTEGFKGPSCKDPVVFSMAPQRSSSRSSWLAPILIALMCVALLVLGYVLYQRNRNKLAALDFSVSFKKPTFGKREGLLEHEHPVSADDQYHAITPQEPGFGNPVFAAPKSQLLTEDGQFKRWVSSDSLQSSDSQEKLTTTFAGPSSSAKQDQVFFFRKS | ||||||
Disulfide bond | 24↔36 | |||||
Sequence: CPQGWFDCQNGRC | ||||||
Disulfide bond | 31↔49 | |||||
Sequence: CQNGRCIAMFWRCDGQNDC | ||||||
Disulfide bond | 43↔58 | |||||
Sequence: CDGQNDCGNHKDETGC | ||||||
Disulfide bond | 85↔100 | |||||
Sequence: CDGEGDCHDSSDELDC | ||||||
Disulfide bond | 110↔128 | |||||
Sequence: CHNNECIPNHWRCDQTEDC | ||||||
Disulfide bond | 122↔137 | |||||
Sequence: CDQTEDCADASDELDC | ||||||
Disulfide bond | 162↔180 | |||||
Sequence: CLDGQCLLPGKVCDGKKDC | ||||||
Disulfide bond | 912↔927 | |||||
Sequence: CDGHKDCADNADEAAC | ||||||
Disulfide bond | 931↔943 | |||||
Sequence: CPSKDFTCQNGKC | ||||||
Disulfide bond | 938↔956 | |||||
Sequence: CQNGKCIDMDWRCDGYDDC | ||||||
Disulfide bond | 950↔965 | |||||
Sequence: CDGYDDCDDQSDEANC | ||||||
Disulfide bond | 970↔982 | |||||
Sequence: CASHQFTCKSGAC | ||||||
Disulfide bond | 977↔995 | |||||
Sequence: CKSGACLPLYWRCDGGRDC | ||||||
Disulfide bond | 989↔1004 | |||||
Sequence: CDGGRDCPDGDDELDC | ||||||
Disulfide bond | 1009↔1021 | |||||
Sequence: CPNGYDRCSNGQC | ||||||
Disulfide bond | 1016↔1034 | |||||
Sequence: CSNGQCIPLDWTCDGHADC | ||||||
Disulfide bond | 1028↔1043 | |||||
Sequence: CDGHADCSDSSDETNC | ||||||
Disulfide bond | 1049↔1061 | |||||
Sequence: CLEGDFHCSNGQC | ||||||
Disulfide bond | 1056↔1074 | |||||
Sequence: CSNGQCVDKRLRCDHDSDC | ||||||
Disulfide bond | 1068↔1083 | |||||
Sequence: CDHDSDCEDDSDESGC | ||||||
Disulfide bond | 1093↔1105 | |||||
Sequence: CVRGMVGCGDGQC | ||||||
Disulfide bond | 1100↔1118 | |||||
Sequence: CGDGQCVYTHDVCDGYADC | ||||||
Disulfide bond | 1112↔1127 | |||||
Sequence: CDGYADCHNGWDEHNC | ||||||
Disulfide bond | 1182↔1194 | |||||
Sequence: CWSDQFQCGSHEC | ||||||
Disulfide bond | 1189↔1207 | |||||
Sequence: CGSHECIAWSSVCDGRTDC | ||||||
Disulfide bond | 1262↔1272 | |||||
Sequence: CLSPGHCSHYC | ||||||
Disulfide bond | 1622↔1632 | |||||
Sequence: CNPVCLNGGHC | ||||||
Disulfide bond | 1643↔1652 | |||||
Sequence: CTEGFKGPSC |
Keywords
- PTM
Family & Domains
Features
Showing features for domain, repeat, region.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 230-269 | EGF-like | ||||
Sequence: DIDECAEQPHICSHGCTNSPGSYKCSCLDGYQLTDNSFCK | ||||||
Repeat | 403-446 | LDL-receptor class B | ||||
Sequence: RFMYWTDWGVKPAVVRSNMDGSNIQRLVSTNLGWPNGLALDHAT | ||||||
Repeat | 447-489 | LDL-receptor class B | ||||
Sequence: NSLYWCDAKLSKLEYLDLATMKRTVVLDESLFHPFALSVFEDT | ||||||
Repeat | 667-708 | LDL-receptor class B | ||||
Sequence: GLLYWVDADKYTLEVCRANGSGHAIVRDDLRRPVGLALYPFA | ||||||
Domain | 1258-1297 | EGF-like | ||||
Sequence: DIDECLSPGHCSHYCQNSKGSFKCTCADGYALGADRRYCK | ||||||
Repeat | 1477-1519 | LDL-receptor class B | ||||
Sequence: LRIYWSDANKNVIESATYQGADRKLVRGTGLSSPFSIALFEDW | ||||||
Domain | 1618-1653 | EGF-like | ||||
Sequence: LGQLCNPVCLNGGHCISEKSSYYCRCTEGFKGPSCK | ||||||
Region | 1766-1792 | Disordered | ||||
Sequence: SSDSLQSSDSQEKLTTTFAGPSSSAKQ |
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length1,801
- Mass (Da)198,912
- Last updated2014-01-22 v1
- ChecksumA42E499E11F27747