U4UUH2 · U4UUH2_DENPD

Function

function

Converts gamma-trimethylaminobutyraldehyde into gamma-butyrobetaine with high efficiency (in vitro). Can catalyze the irreversible oxidation of a broad range of aldehydes to the corresponding acids in an NAD-dependent reaction, but with low efficiency. Catalyzes the oxidation of aldehydes arising from biogenic amines and polyamines.

Catalytic activity

Features

Showing features for active site.

TypeIDPosition(s)Description
Active site247

GO annotations

AspectTerm
Molecular Functionbetaine-aldehyde dehydrogenase activity
Molecular Functionmetal ion binding
Biological Processglycine betaine biosynthetic process from choline

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    4-trimethylaminobutyraldehyde dehydrogenase
  • EC number
  • Alternative names
    • Aldehyde dehydrogenase family 9 member A1
    • Formaldehyde dehydrogenase
    • Gamma-aminobutyraldehyde dehydrogenase

Gene names

    • ORF names
      D910_01385

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Ecdysozoa > Arthropoda > Hexapoda > Insecta > Pterygota > Neoptera > Endopterygota > Coleoptera > Polyphaga > Cucujiformia > Curculionidae > Scolytinae > Dendroctonus

Accessions

  • Primary accession
    U4UUH2

Proteomes

PTM/Processing

Keywords

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain12-474Aldehyde dehydrogenase

Sequence similarities

Belongs to the aldehyde dehydrogenase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    485
  • Mass (Da)
    52,353
  • Last updated
    2013-12-11 v1
  • Checksum
    F67CFE82328F04E0
MQKLYIDGRYQDSTGGETFPAINPANGETLAEVASATREDLDRAVVAAQKGQKIWAAMTAMQRSRILRKAVDILRDRNDELAQIETLDTGKPLSETTAVDIVTGADVLEYYAGLIPAIEGQQIPLRDSAFVYTRREPLGVVAGIGAWNYPIQIALWKSAPALAAGNAMIFKPSEVTSLTALKLAEIYTAAGVPDGVFSVLTGKGAEIGQYLTEHPGIAKISFTGGVVTGKKVMASASASTLKEVTMELGGKSPLIVFPDADLDKAADIAMMANFYSSGQVCTNGTRVFVPKTLQGEFEAKILERVKRIKLGQPTDEAVNFGPLVSFAHMENVLRFIDSGKREGARLLIGGERVTSGEYGKGAFVAPTVFTDCRDEMEIVREEIFGPVMSILTYESEDEVIRRANDTDYGLAAGLVTRDLNTAHRVIHQLEAGICWINTWGESAAEMPVGGYKHSGVGRENGVSTLEHYTQIKSVQVELGEFSSVF

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
KI210216
EMBL· GenBank· DDBJ
ERL96198.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
FeedbackHelp