U4QFT4 · U4QFT4_LACHE
- ProteinThreonine--tRNA ligase
- GenethrS
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids644 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
Catalytic activity
- tRNA(Thr) + L-threonine + ATP = L-threonyl-tRNA(Thr) + AMP + diphosphate + H+
Cofactor
Note: Binds 1 zinc ion per subunit.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 334 | Zn2+ (UniProtKB | ChEBI); catalytic | |||
Binding site | 385 | Zn2+ (UniProtKB | ChEBI); catalytic | |||
Binding site | 515 | Zn2+ (UniProtKB | ChEBI); catalytic | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | ATP binding | |
Molecular Function | metal ion binding | |
Molecular Function | threonine-tRNA ligase activity | |
Molecular Function | transferase activity | |
Molecular Function | tRNA binding | |
Biological Process | threonyl-tRNA aminoacylation |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameThreonine--tRNA ligase
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Bacillota > Bacilli > Lactobacillales > Lactobacillaceae > Lactobacillus
Accessions
- Primary accessionU4QFT4
Proteomes
Subcellular Location
Interaction
Subunit
Homodimer.
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 1-62 | TGS | |||
Domain | 271-538 | Aminoacyl-transfer RNA synthetases class-II family profile | |||
Sequence similarities
Belongs to the class-II aminoacyl-tRNA synthetase family.
Family and domain databases
Sequence
- Sequence statusComplete
- Length644
- Mass (Da)73,375
- Last updated2013-12-11 v1
- Checksum14BFF7506CBC8D2F
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CBUH010000171 EMBL· GenBank· DDBJ | CDI43432.1 EMBL· GenBank· DDBJ | Genomic DNA |