U3PWP1 · U3PWP1_9VIRU

Function

function

RNA-dependent RNA polymerase which is found both free and covalently attached to the genomic RNA. May also contain guanylyl and methyl transferase activities.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Molecular FunctionRNA-dependent RNA polymerase activity
Biological Processviral genome replication

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    RNA-directed RNA polymerase
  • EC number
  • Alternative names
    • Protein VP1

Organism names

Accessions

  • Primary accession
    U3PWP1

Interaction

Subunit

Interacts with VP3 in the cytoplasm.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain1-556Birnavirus RNA-directed RNA polymerase palm
Domain580-703RNA-directed RNA polymerase thumb

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    998
  • Mass (Da)
    113,222
  • Last updated
    2013-12-11 v1
  • Checksum
    7051E59A68D4545A
MSDIFNQQGLKSKFSSIIKGENQEGNDIRDVFNSFTDVMLEAVEDLEYTDLGDALLENSVKVFRPRPYDELINVPFTEAASPRMLDLYEEQLGSKDVSLPIGAEQILPTYKPGHEITPPLTTLANSLAFEYMKYIEGSSNPDFDAAIYRTIKELLEIQGNTRFSTGSLMGQVRRIAAGQDVAYGRNGHHKNKSFKELGLTPYKVMGWLDEYMPIREGEPDFKLTNTLDWLVYTPQEAELMGVPDSLPAISHSSAAGLPWLGKKKGEVAISALITANMLIQDTSRILKETLFSGSNDPLEAKKEGVAAETAKSKKRSAGQFSAEILKMITTEYSYTMMGLLFPKGERYHRADHLNKTRNIWSASYVTHLLGSIISDQPAKRMLNVITSSEPTPSLAKFSPTQGGMNTLVETILEATDIMELVYADNAYMYFPDEDVWYSIDLTKGEANCTRDVAMTTAMYLLTRGWTSNEGVPLYNYTWAYLALYMIPYTTVDSISILKNFQIKNPGQGSGNPWTFLNNHVLTTILMNKWRAMGRPKPTAQVIEKLSSETGIDFKVELVVPDFKKKLLEAKDRSLPVEDRVKPRTIVTMDMLGWDVTHTQYGFTPVLAKERLFKSIACPQPPSSTFSSSIAKQVHKYIQNVALLYVGGWAYPCIAQTIEGYALNHWNTIDSMLRNNPNYDLEKALVKAVDTSPFAEVMALINIRKPMHEQNYAAVLYTPKERPRVDPKRLRSNPFLIREGENVSQYTRRMAKIRQENDMVSEEWAPIKGLISRLFAREALGENIKLRENFSKGKIREIMSSIEQQLKERGLGLEVWYQAYATNTPPKGLSGNLAQLLVSLTPPRSQSLPREVFRKLLDYDPVGSGRTPDLTSDERYYYDLQSLEHNRIEYLRKLNEDDISIFANKYMVYSSTLLSTMLPDKVEWPEQRSMKVQDAKDPFMVKGFKARDMKPRFGAEILEEELLPAKKSSTEKRRMQRKGQKLKLQRQAADGKFVVQRLN

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
KF298272
EMBL· GenBank· DDBJ
AGW51763.1
EMBL· GenBank· DDBJ
Genomic RNA

Similar Proteins

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