U3PSR1 · U3PSR1_9VIRU

Function

function

The precursor of VP2 plays an important role in capsid assembly. First, pre-VP2 and VP2 oligomers assemble to form a procapsid. Then, the pre-VP2 intermediates may be processed into VP2 proteins by proteolytic cleavage mediated by VP4 to obtain the mature virion. The final capsid is composed of pentamers and hexamers but VP2 has a natural tendency to assemble into all-pentameric structures. Therefore pre-VP2 may be required to allow formation of the hexameric structures.

Features

Showing features for active site.

110571002003004005006007008009001,000
TypeIDPosition(s)Description
Active site630Nucleophile
Active site673

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcytoplasm
Cellular Componenthost cell cytoplasm
Cellular Componentviral capsid
Molecular Functionmetal ion binding
Molecular Functionserine-type peptidase activity
Molecular Functionstructural molecule activity
Biological Processproteolysis

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Structural polyprotein

Organism names

Accessions

  • Primary accession
    U3PSR1

Subcellular Location

Keywords

Family & Domains

Features

Showing features for domain, region.

TypeIDPosition(s)Description
Domain503-726Peptidase S50
Region709-730Disordered

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    1,057
  • Mass (Da)
    116,314
  • Last updated
    2013-12-11 v1
  • Checksum
    B3B7C16029D1A798
MKMNTSNEYLKTLLNPTQFISDIPDDIMIRHINRSETITYNLKSGTSGTGLIVFYPNTPSSIAGFHYKWDATNSVWVFDQYIYTAQELKKSYDYGRLISGAVSVKSSTLPAGVYALNGTFNAVWFQGTLSEVTDLNYDRILSITSNPLDKVGNVLVGDGLAILSLPQGFNNPYVRLGDESPSSLTSVTHITNTSQNLGYGGAFSVPQTKVAGQATFVKEFNINVDSVGPIDVTWSGQMTMQDEWTVTANYQPLNLSGTLITGSMRTIIWSNVGVSNGAHYMNLNEMNVSFFHENPPPEPVAAIKVHLTFGNNTNGESTMKVDGSFTFHVVGGATIGVNSPTVMIGYQGVAEGTAITISGVNNYELVPNPALQKNLPMTYGTCDPTDLTYVKYILSHRERLGIRSVMTLADYARLKMQMHVMTEYRVDDREAASFDFWNLLKQIKKLAVPVASTMLPQFAPIIGAADNLANAVMGNSASGQPIGNSASGLPISMTRRIKSAHSADTPIGESNWKPNESAEFNKLDVIYDVSHSSMALFPVIMMDNDQVVPSDPEELFIAVSLTESLRKQIPGIDEMPYYTVGGHRVYNAVSNGQLSTAPFLTSDYILLPCYQLFDGKLATSLTPNRVTGTSHQLALYAAEGLQKRGITGKAPYAAFTGSVAGQSVGEVFGINLKSRLTDSLGIPLYGNSKGLKPVPDLYQLEKLLGVSGDVPRRTPRETPSHWTASSTSNPFVSTNPFLNGNADQEDAQPLRTPKANPFLDDDQDVGEVPPQRMAKLISEDTRKAFLEDGQSIPSSQEKIVTVHDFLLRNQELLEAMFGLISRGHEKALVNMVTKAAINISSQAKELTEDRIARLEVKLQNLARQGIVLDLENVKRVGRITQEDTQAAIMRSKDQQMRTKLRRVFLNNVSIGREYTEDEFVEFWVRQGFIPNGLQISAWLKDEDWTSPTPVLSKRHYDSYLQMLGPSPDPGLVEQVRIMVDNVYDENGNKGPTQDQARMLSSSVRRLISQSLVTRPQPTPKVPVRKIASIATGQDANPDRRAALERLRRARGDDSEIL

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
KF298271
EMBL· GenBank· DDBJ
AGW51761.1
EMBL· GenBank· DDBJ
Genomic RNA

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