U3N7D8 · U3N7D8_DANRE
- ProteinTransient receptor potential cation channel subfamily c member 4a
- Genetrpc4b
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids915 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score3/5
Function
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | cation channel complex | |
Cellular Component | plasma membrane | |
Molecular Function | inositol 1,4,5 trisphosphate binding | |
Molecular Function | monoatomic cation channel activity | |
Molecular Function | store-operated calcium channel activity | |
Biological Process | calcium ion transmembrane transport | |
Biological Process | monoatomic cation transport | |
Biological Process | regulation of cytosolic calcium ion concentration |
Keywords
- Molecular function
- Biological process
- Ligand
Names & Taxonomy
Protein names
- Submitted names
Gene names
Organism names
- Strains
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Ostariophysi > Cypriniformes > Danionidae > Danioninae > Danio
Accessions
- Primary accessionU3N7D8
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 330-350 | Helical | ||||
Sequence: LITCVFIGLMFPLLSLCYLVA | ||||||
Transmembrane | 362-383 | Helical | ||||
Sequence: PFIKFICHTASYLTFLFLLLLA | ||||||
Transmembrane | 404-422 | Helical | ||||
Sequence: WMILPWVLGFIWTEIKQMW | ||||||
Transmembrane | 434-454 | Helical | ||||
Sequence: WNLMDFVMNSLYLATISLKIV | ||||||
Transmembrane | 475-496 | Helical | ||||
Sequence: LVAEAVFAIANIFSSLRLISLF | ||||||
Transmembrane | 516-540 | Helical | ||||
Sequence: ILKFLFIYCLVLLAFANGLNQLYFY | ||||||
Transmembrane | 561-583 | Helical | ||||
Sequence: FSTLFETLQSLFWSIFGLISLYV | ||||||
Transmembrane | 595-617 | Helical | ||||
Sequence: FVGATMFGTYNVISLVVLLNMLI |
Keywords
- Cellular component
PTM/Processing
Features
Showing features for disulfide bond.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Disulfide bond | 549↔554 | |||||
Sequence: CKGIRC |
Structure
Family & Domains
Features
Showing features for repeat, domain, region, compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Repeat | 141-173 | ANK | ||||
Sequence: PDITPIILAAHTNNYEIIKMLVQKGVSVPQPHE | ||||||
Domain | 176-238 | Transient receptor ion channel | ||||
Sequence: CNCVECVSSSDVDSLRHSRSRLNIYKALASPSLIALSSEDPFLTAFQLSWELQELSKVENEFK | ||||||
Region | 756-779 | Disordered | ||||
Sequence: NRKSTRANKSDTSASDVSHPEGSL | ||||||
Compositional bias | 762-779 | Polar residues | ||||
Sequence: ANKSDTSASDVSHPEGSL |
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length915
- Mass (Da)105,154
- Last updated2013-12-11 v1
- Checksum58DCE8CAA67CC7F4
Computationally mapped potential isoform sequences
There is 1 potential isoform mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A0A0R4IM91 | A0A0R4IM91_DANRE | trpc4b | 915 |
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 762-779 | Polar residues | ||||
Sequence: ANKSDTSASDVSHPEGSL |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
KF446631 EMBL· GenBank· DDBJ | AGW27448.1 EMBL· GenBank· DDBJ | mRNA |