U3LU74 · U3LU74_9AVES
- ProteinCytochrome b
- Genecytb
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids380 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
Cofactor
Protein has several cofactor binding sites:
Note: Binds 2 heme groups non-covalently.
Note: Binds 2 heme groups non-covalently.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 84 | Fe (UniProtKB | ChEBI) of heme b b562 (UniProtKB | ChEBI); axial binding residue | ||||
Sequence: H | ||||||
Binding site | 98 | Fe (UniProtKB | ChEBI) of heme b b566 (UniProtKB | ChEBI); axial binding residue | ||||
Sequence: H | ||||||
Binding site | 183 | Fe (UniProtKB | ChEBI) of heme b b562 (UniProtKB | ChEBI); axial binding residue | ||||
Sequence: H | ||||||
Binding site | 197 | Fe (UniProtKB | ChEBI) of heme b b566 (UniProtKB | ChEBI); axial binding residue | ||||
Sequence: H | ||||||
Binding site | 202 | a ubiquinone (UniProtKB | ChEBI) | ||||
Sequence: H |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | mitochondrial inner membrane | |
Cellular Component | respiratory chain complex III | |
Molecular Function | metal ion binding | |
Molecular Function | ubiquinol-cytochrome-c reductase activity | |
Biological Process | respiratory electron transport chain |
Keywords
- Biological process
- Ligand
Names & Taxonomy
Protein names
- Recommended nameCytochrome b
Gene names
Encoded on
- Mitochondrion
Organism names
- Organism
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Archelosauria > Archosauria > Dinosauria > Saurischia > Theropoda > Coelurosauria > Aves > Neognathae > Procellariiformes > Procellariidae > Pterodroma
Accessions
- Primary accessionU3LU74
Subcellular Location
UniProt Annotation
GO Annotation
Membrane ; Multi-pass membrane protein
Mitochondrion inner membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 31-57 | Helical | ||||
Sequence: WWNFGSLLGICLMTQILTGLLLAMHYT | ||||||
Transmembrane | 78-99 | Helical | ||||
Sequence: WLIRNLHANGASFFFICIYLHI | ||||||
Transmembrane | 114-134 | Helical | ||||
Sequence: WNTGVMLLLTLMATAFVGYVL | ||||||
Transmembrane | 141-159 | Helical | ||||
Sequence: FWGATVITNLFSAIPYIGQ | ||||||
Transmembrane | 179-201 | Helical | ||||
Sequence: FFALHFLLPFAIPGLTLIHLTFL | ||||||
Transmembrane | 230-251 | Helical | ||||
Sequence: ILGFMFMLLPLTALALFSPNLL | ||||||
Transmembrane | 289-309 | Helical | ||||
Sequence: LGGVLALAASVLILFLTPFLH | ||||||
Transmembrane | 321-341 | Helical | ||||
Sequence: LSQLLFWILVANLLILTWVGS | ||||||
Transmembrane | 347-373 | Helical | ||||
Sequence: PFIIIGQLASLTYFTILLILFPIIGAL |
Keywords
- Cellular component
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 1-210 | Cytochrome b/b6 N-terminal region profile | ||||
Sequence: MAPNLRKSHPLLKMVNNSLIDLPTPSNISAWWNFGSLLGICLMTQILTGLLLAMHYTADTTLAFSSVAHTCRNVQYGWLIRNLHANGASFFFICIYLHIGRGFYYGSYLYKETWNTGVMLLLTLMATAFVGYVLPWGQMSFWGATVITNLFSAIPYIGQTLVEWAWGGFSVDNPTLTRFFALHFLLPFAIPGLTLIHLTFLHESGSNNPL | ||||||
Domain | 211-380 | Cytochrome b/b6 C-terminal region profile | ||||
Sequence: GVVSNCDKIPFHPYFTLKDILGFMFMLLPLTALALFSPNLLGDPENFTPANPLITPPHIKPEWYFLFAYAILRSIPNKLGGVLALAASVLILFLTPFLHKAKQRTMTFRPLSQLLFWILVANLLILTWVGSQPVEHPFIIIGQLASLTYFTILLILFPIIGALENKMLNY |
Sequence similarities
Belongs to the cytochrome b family.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length380
- Mass (Da)42,681
- Last updated2013-12-11 v1
- Checksum93FE4B2D39A6AA84