U3KTI7 · U3KTI7_9HEXA
- ProteinNADH-ubiquinone oxidoreductase chain 1
- GeneND1
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids317 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
Catalytic activity
- a ubiquinone + NADH + 5 H+(in) = a ubiquinol + NAD+ + 4 H+(out)
a ubiquinone RHEA-COMP:9565 + CHEBI:57945 + 5 H+ (in)CHEBI:15378= a ubiquinol RHEA-COMP:9566 + CHEBI:57540 + 4 H+ (out)CHEBI:15378
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | mitochondrial inner membrane | |
Molecular Function | NADH dehydrogenase (ubiquinone) activity | |
Molecular Function | NADH dehydrogenase activity | |
Biological Process | aerobic respiration |
Keywords
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameNADH-ubiquinone oxidoreductase chain 1
- EC number
Gene names
Encoded on
- Mitochondrion
Organism names
- Organism
- Taxonomic lineageEukaryota > Metazoa > Ecdysozoa > Arthropoda > Hexapoda > Diplura > Rhabdura > Projapygoidea > Octostigmatidae > Octostigma
Accessions
- Primary accessionU3KTI7
Subcellular Location
UniProt Annotation
GO Annotation
Mitochondrion inner membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Transmembrane | 6-25 | Helical | |||
Transmembrane | 74-91 | Helical | |||
Transmembrane | 103-122 | Helical | |||
Transmembrane | 143-163 | Helical | |||
Transmembrane | 175-194 | Helical | |||
Transmembrane | 223-245 | Helical | |||
Transmembrane | 251-271 | Helical | |||
Transmembrane | 292-315 | Helical | |||
Keywords
- Cellular component
Structure
Sequence
- Sequence statusComplete
- Length317
- Mass (Da)36,042
- Last updated2013-12-11 v1
- Checksum21F2EFFF63E5C95C
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
JN990598 EMBL· GenBank· DDBJ | AEV44846.1 EMBL· GenBank· DDBJ | Genomic DNA |