U3IE63 · U3IE63_ANAPP

Function

Catalytic activity

Features

Showing features for binding site, active site.

113731002003004005006007008009001,0001,1001,2001,300
TypeIDPosition(s)Description
Binding site859-866ATP (UniProtKB | ChEBI)
Binding site886ATP (UniProtKB | ChEBI)
Active site1043Proton acceptor
Binding site1047ATP (UniProtKB | ChEBI)
Binding site1048Mg2+ (UniProtKB | ChEBI)
Binding site1061Mg2+ (UniProtKB | ChEBI)

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcytosol
Cellular Componentnucleoplasm
Cellular Componentplasma membrane
Cellular Componentreceptor complex
Molecular FunctionATP binding
Molecular Functiongrowth factor binding
Molecular Functionmetal ion binding
Molecular Functionprotein homodimerization activity
Molecular Functionprotein phosphatase binding
Molecular Functionvascular endothelial growth factor receptor activity
Biological Processangiogenesis
Biological Processlymphangiogenesis
Biological Processnegative regulation of apoptotic process
Biological Processpositive regulation of endothelial cell migration
Biological Processpositive regulation of endothelial cell proliferation
Biological Processpositive regulation of ERK1 and ERK2 cascade
Biological Processpositive regulation of JNK cascade
Biological Processpositive regulation of protein kinase C signaling
Biological Processpositive regulation of protein phosphorylation
Biological Processpositive regulation of vascular endothelial growth factor production
Biological Processvascular endothelial growth factor receptor signaling pathway

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Vascular endothelial growth factor receptor 3
  • EC number

Gene names

    • Name
      FLT4

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Archelosauria > Archosauria > Dinosauria > Saurischia > Theropoda > Coelurosauria > Aves > Neognathae > Galloanserae > Anseriformes > Anatidae > Anatinae > Anas

Accessions

  • Primary accession
    U3IE63

Proteomes

Subcellular Location

Membrane
; Single-pass type I membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane783-807Helical

Keywords

  • Cellular component

PTM/Processing

Keywords

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain, region.

TypeIDPosition(s)Description
Domain248-329Ig-like
Domain334-417Ig-like
Domain424-560Ig-like
Domain563-678Ig-like
Domain685-771Ig-like
Domain852-1179Protein kinase
Region1292-1321Disordered
Region1342-1373Disordered

Sequence similarities

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    1,373
  • Mass (Da)
    155,783
  • Last updated
    2019-09-18 v2
  • Checksum
    35002B31D2BC24FA
MFASSLFSFLSPDLVSSYSMTPPALSITEEEHVINAKDTLTITCRGQHPLEWSWPGGKVDPTGKEKEMEFMASAAPSAGRAIREEDCEGTGTKPYCKVLVLTETQANDTGYYRCYYKYIDAKIEGTTAVSAYVFVRDYEQPFINKPETLLISKKENTWVPCLVSIPDLNVTLILQNSLIHPDRKSVFWDNKKGVQVPTHLIRDSLFVQCETVIDKKVFKSNFFIIHIAGSELYDIQLYPKKAMELLVGEKLVLNCTVWAEFNSGVRFQWTYPGKQTQRAVIEPERRSLQTHTELSSILTLHNVSQQDLGKYTCTATNGAQMLEESTDVIVHEKPFINVEWRKGPVIEATAGDEAVKLPVKVVAYPPPDFQWYKDGKLIPKQSQSSMQIKDVSEQHAGTYTLVLRNRLAGLEKRISLQLIVNVPPRIHEKEASSPSIYSRRSSQALTCTVYGIPAPEVIQWQWRPWMPCRMFSRRSLNSRHRAARRHQRDRMPECKDWKDVSQQDAVNPIESIDTWVEFVEGRNKTVSKLAIQEANVSAMYKCIASNKVGRDERLIYFYVTTIPDGFEIESQPSEEPIEGQDLQLSCNADNYTYENLQWYRLNLSKLHDEEGNPLVLDCKNVHHYATKMQGELRFQPDSNDATLLLTIPNISLGEEGDYVCEVQNRKTREKHCHKKYISVQALEIPRLKQNLTDIWVNVSDSIEMRCKVDGNHVPDISWYKDEKLVEEVSGIDLADFNQRLSIQRVREEDAGLYLCSVCNAKGCVNSSASVSVEGSDDRTNVEIVILIGTGVIAVFFWILLILIFCNIKRPAHADIKTGYLSIIMDPGEVPLEEQCEYLPYDSSKWEFPRDRLRLGKVLGHGAFGKVVEASAFGINKSNSCETVAVKMLKEGATASEHKALMSELKILIHIGNHLNVVNLLGACTKPNGPLMVIVEFCKYGNLSNYLRTKREGFSPYREKSPRLRIQVQSIVEAVRADRRSRSRTSDSAIFNRFLMHKSQTAQPIQEVDDLWQSPLTMEDLICYSFQVARGMEFLASRKCIHRDLAARNILLSENNVVKICDFGLARDIYKDPDYVRKGSARLPLKWMAPESIFDKVYTTQSDVWSFGVLLWEIFSLGASPYPGVQINEEFCQRLKDGTRMRAPEYATAEIYRIMLSCWHGDPKERPTFSDLVEILGNLLQENVQQEGKDYIPLNDSHSSEDDGFCQVPSSAQQNSDEEDFDMRIRCHSLAARYYNCVSFPGCLTGGNQIRCPSRIKTFEEFPMTHTMYKAHPDNQTDSGMVLASEEFERIENRHRKEGGFSSKGPSRTAELPGEQSDLRGRCRPLYGSQVGGQTFYNSEYGELSEHSEDGSCTPPGEGASPPALHASFFSEQY

Keywords

Genome annotation databases

Similar Proteins

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