U3I4K2 · U3I4K2_ANAPP

Function

Catalytic activity

  • (2E)-hexadecenal + H2O + NAD+ = (E)-hexadec-2-enoate + 2 H+ + NADH
  • (2E,6E)-farnesal + H2O + NAD+ = (2E,6E)-farnesoate + 2 H+ + NADH
    EC:1.2.1.94 (UniProtKB | ENZYME | Rhea)
  • 2 H+ + hexadecanoate + NADH = H2O + hexadecanal + NAD+
  • 2,6,10,14-tetramethylpentadecanal + H2O + NAD+ = 2,6,10,14-tetramethylpentadecanoate + 2 H+ + NADH
  • 22-oxodocosanoate + H2O + NAD+ = docosanedioate + 2 H+ + NADH
  • H2O + NAD+ + octadecanal = 2 H+ + NADH + octadecanoate
  • H2O + NAD+ + octanal = 2 H+ + NADH + octanoate
  • H2O + NAD+ + tetradecanal = 2 H+ + NADH + tetradecanoate
  • H2O + heptanal + NAD+ = 2 H+ + heptanoate + NADH
  • a fatty aldehyde + H2O + NAD+ = a fatty acid + 2 H+ + NADH
  • an aldehyde + H2O + NAD+ = a carboxylate + 2 H+ + NADH
    EC:1.2.1.3 (UniProtKB | ENZYME | Rhea)
  • decanal + H2O + NAD+ = decanoate + 2 H+ + NADH
  • dodecanoate + 2 H+ + NADH = dodecanal + H2O + NAD+

Features

Showing features for active site.

TypeIDPosition(s)Description
Active site210
Active site244

GO annotations

AspectTerm
Cellular Componentendoplasmic reticulum membrane
Molecular Functionoxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
Biological Processcellular aldehyde metabolic process
Biological Processfatty acid metabolic process

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Aldehyde dehydrogenase

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Archelosauria > Archosauria > Dinosauria > Saurischia > Theropoda > Coelurosauria > Aves > Neognathae > Galloanserae > Anseriformes > Anatidae > Anatinae > Anas

Accessions

  • Primary accession
    U3I4K2

Proteomes

Subcellular Location

Endoplasmic reticulum membrane
; Single-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane465-483Helical

Keywords

Interaction

Subunit

Homodimer.

Family & Domains

Features

Showing features for domain, coiled coil.

TypeIDPosition(s)Description
Domain3-425Aldehyde dehydrogenase
Coiled coil23-50

Sequence similarities

Belongs to the aldehyde dehydrogenase family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    510
  • Mass (Da)
    56,484
  • Last updated
    2019-06-05 v2
  • Checksum
    2954EE9120449A2A
MERMQQVVGRARAAFSSGRCRSLEFRLQQLKNLERMVREKEKEILAALQSDLHKCGHNAYSHEVMGVLGELAQAMENLPSWAAPQPVKKNLLTMRDEAYIYPEPLGVVLVIGAWNYPFMLVVQPLIGAIAAGNAVVVKPSEVSEHTSQLLADLLPQYLDEELYPVVTGGVPETTELLKQRFDHILYTGNTAVGKIVMAAAAKHLTPVTLELGGKSPCYIDKDCDLAVACRRITWGKYMNCGQTCIAPDYILCEPSIQSQVVENIKATLQEFYGEDVKKSPDYERIVNKRHFRRIVSLLEGQKIAHGGETDEASCFIAPTILTDVSAESKVMEEEIFGPVLPIVSVKGVDEAIEFINSREKPLALYVFSNDKKVIKRVISETSSGGVTGNDVIMHFFLSTLPFGGVGNSGMGAYHGKHSFETFSHHRACLIKDLKMEGTNKLRYPPGSQKKLDWAKFFVLKRFNKGRLGLIFLALLGVVAAVVIKSHQSVLKRKALLIVLAVQRLGWLSGC

Computationally mapped potential isoform sequences

There are 4 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
A0A493U1U7A0A493U1U7_ANAPP512
A0A493T3P1A0A493T3P1_ANAPP490
U3I679U3I679_ANAPP487
A0A493T008A0A493T008_ANAPP488

Keywords

Genome annotation databases

Similar Proteins

Disclaimer

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