U2NZJ1 · U2NZJ1_LEVBR

Function

function

Cell wall formation.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Protein has several cofactor binding sites:
Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Mn2+ (UniProtKB | Rhea| CHEBI:29035 )

Note: Binds 2 magnesium or manganese ions per subunit.
Mn2+ (UniProtKB | Rhea| CHEBI:29035 )

Pathway

Cell wall biogenesis; peptidoglycan biosynthesis.

Features

Showing features for active site, binding site.

TypeIDPosition(s)Description
Active site23
Active site192
Binding site306Mg2+ 1 (UniProtKB | ChEBI)
Binding site319Mg2+ 2 (UniProtKB | ChEBI)
Binding site319Mg2+ 1 (UniProtKB | ChEBI)
Binding site321Mg2+ 2 (UniProtKB | ChEBI)
Active site330

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular FunctionATP binding
Molecular FunctionD-alanine-D-alanine ligase activity
Molecular Functionmetal ion binding
Biological Processcell wall organization
Biological Processpeptidoglycan biosynthetic process
Biological Processregulation of cell shape

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    D-alanine--D-alanine ligase
  • EC number
  • Alternative names
    • D-Ala-D-Ala ligase
    • D-alanylalanine synthetase

Gene names

    • Name
      ddl
    • ORF names
      HMPREF0495_01446

Organism names

Accessions

  • Primary accession
    U2NZJ1

Proteomes

Subcellular Location

Keywords

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain146-352ATP-grasp

Sequence similarities

Belongs to the D-alanine--D-alanine ligase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    384
  • Mass (Da)
    42,329
  • Last updated
    2013-11-13 v1
  • Checksum
    2B0F4828893C4BBC
MSGKMETKTKLHVGLLFGGNSSEHDVSKRSAHNIYDAMDKDRYNVSLFLLTRDGFVLSDAASRRVFDGEDEATVAAEEQAKVDASNPLAPIWNLSQAKDIDVFFPIIHGNLGEDGTIQGLFRLLKKPFVGSGVLASAVSFDKDMTKQVLTAHGIRNTKYVVLTPDNRADFDYATIQSRLGDNVFIKPANQGSSVGIHKASNAQEYLDGVADAFRYDYKVLVEQTIDGPQEVEISILGNEQPQASKLGAIRVPESDVFYDYNNKFVDASGVTFEVPVKLSDELTQEITQMGLQTYAALGLKGMARIDYLVSKDGVPYVGEVNTLPGFTNISLYPQLWQATGINYADLIDRLIELALSEFHYQDELAYDFIPLDDHSAASTYKPKA

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AWVK01000057
EMBL· GenBank· DDBJ
ERK43565.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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