U1MSJ2 · U1MSJ2_9MICO

Function

function

Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Pathway

Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 4/5.

Features

Showing features for binding site, site.

TypeIDPosition(s)Description
Binding site10substrate
Binding site10-11ATP (UniProtKB | ChEBI)
Binding site18ATP (UniProtKB | ChEBI)
Site18Transition state stabilizer
Binding site42substrate
Binding site78substrate
Binding site92substrate
Binding site93-95ATP (UniProtKB | ChEBI)
Binding site103ATP (UniProtKB | ChEBI)
Binding site127-133ATP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctionATP binding
Molecular Functionpantetheine-phosphate adenylyltransferase activity
Biological Processcoenzyme A biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Phosphopantetheine adenylyltransferase
  • EC number
  • Alternative names
    • Dephospho-CoA pyrophosphorylase
    • Pantetheine-phosphate adenylyltransferase
      (PPAT
      )

Gene names

    • Name
      coaD
    • ORF names
      L332_04045

Organism names

  • Taxonomic identifier
  • Strain
    • RW1
  • Taxonomic lineage
    Bacteria > Actinomycetota > Actinomycetes > Micrococcales > Microbacteriaceae > Agrococcus

Accessions

  • Primary accession
    U1MSJ2

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

Homohexamer.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain7-137Cytidyltransferase-like

Sequence similarities

Belongs to the bacterial CoaD family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    160
  • Mass (Da)
    17,598
  • Last updated
    2013-11-13 v1
  • Checksum
    9B335BDC86F23162
MPRIAVVPGSFDPVTLGHLDVVARAARIFDEVHVVVTHNPDKHAFLPVVEREALIERSIEEARIEGQIRIANWSMGLLVDYCQQVGAEVLVKGIRSSTDLSYETPMSIVNRNLAGVETIFMLPNPENAHVSSSLVRQVSELGGDISPYVPRAVATFLQSR

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
ASHR01000030
EMBL· GenBank· DDBJ
ERG63625.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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