T2SZH9 · T2SZH9_HELPX

Function

function

Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

a divalent metal cation (UniProtKB | Rhea| CHEBI:60240 )

Features

Showing features for active site, binding site.

TypeIDPosition(s)Description
Active site80Proton acceptor
Binding site80-81NAD+ (UniProtKB | ChEBI)
Binding site149-150NAD+ (UniProtKB | ChEBI)
Binding site177NAD+ (UniProtKB | ChEBI)
Binding site179NAD+ (UniProtKB | ChEBI)
Binding site187NAD+ (UniProtKB | ChEBI)
Binding site190-195NAD+ (UniProtKB | ChEBI)
Binding site246NAD+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctionATP binding
Molecular Functionmetal ion binding
Molecular FunctionNAD binding
Molecular FunctionNAD+ kinase activity
Biological ProcessNAD metabolic process
Biological ProcessNADP biosynthetic process
Biological Processphosphorylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    NAD kinase
  • EC number
  • Alternative names
    • ATP-dependent NAD kinase

Gene names

    • Name
      nadK
    • ORF names
      L930_08490

Organism names

  • Taxonomic identifier
  • Strain
    • PZ5004
  • Taxonomic lineage
    Bacteria > Campylobacterota > Epsilonproteobacteria > Campylobacterales > Helicobacteraceae > Helicobacter

Accessions

  • Primary accession
    T2SZH9

Proteomes

Subcellular Location

Keywords

Family & Domains

Sequence similarities

Belongs to the NAD kinase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    294
  • Mass (Da)
    32,931
  • Last updated
    2013-11-13 v1
  • Checksum
    FE876F7EFD94272B
MFQALSYNIRMKDSHQTIGVFVRPTHYQNPLFEELERAKEWVLKLLEDEGFESFMVDSLDGAKDERLIEKADAFLCLGGDGTILGALRMTHSYNKPCFGVRIGNLGFLSAVELNGLKDFLQDLKQDRIKLEEHLALEGRIGKISFYAINEIVIAKKKALGVLDIKAYAGHTPFNTYKGDGLIIATPLGSTAYNLSAHGPIVHALSQSYILTPLCDFSLTQRPLVLGAEFCLNFCAHEDALVVIDGQATYDLKANQPLYIQKSPTTTKLLQKNSRDYFKVLKEKLLWGESPSKKR

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
ASZF01000211
EMBL· GenBank· DDBJ
EQD96949.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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