T2CSA0 · T2CSA0_HV1
- ProteinEnvelope glycoprotein gp160
- Geneenv
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids865 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | host cell endosome membrane | |
Cellular Component | host cell plasma membrane | |
Cellular Component | plasma membrane | |
Cellular Component | viral envelope | |
Cellular Component | virion membrane | |
Molecular Function | structural molecule activity | |
Biological Process | apoptotic process | |
Biological Process | clathrin-dependent endocytosis of virus by host cell | |
Biological Process | fusion of virus membrane with host endosome membrane | |
Biological Process | virus-mediated perturbation of host defense response |
Keywords
- Biological process
Names & Taxonomy
Protein names
- Recommended nameEnvelope glycoprotein gp160
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageViruses > Riboviria > Pararnavirae > Artverviricota > Revtraviricetes > Ortervirales > Retroviridae > Orthoretrovirinae > Lentivirus
- Virus hosts
Accessions
- Primary accessionT2CSA0
Subcellular Location
UniProt Annotation
GO Annotation
Host cell membrane ; Peripheral membrane protein
Host cell membrane ; Single-pass type I membrane protein
Host endosome membrane ; Peripheral membrane protein
Host endosome membrane ; Single-pass type I membrane protein
Virion membrane ; Peripheral membrane protein
Virion membrane ; Single-pass type I membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 12-38 | Helical | ||||
Sequence: TWGILGFWIILSCSVVGNLWVTVYYGV | ||||||
Transmembrane | 521-544 | Helical | ||||
Sequence: AVGIGAVFLGFLGTAGSTMGAASI | ||||||
Transmembrane | 687-714 | Helical | ||||
Sequence: WLWYIRIFVMIVGGLIGLRIIFAVLSIV |
Keywords
- Cellular component
PTM/Processing
Keywords
- PTM
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 30-520 | Human immunodeficiency virus 1 envelope glycoprotein Gp120 | ||||
Sequence: LWVTVYYGVPVWKEAKATLFCASDAKAYEKEVHNVWATHACVPTDPNPQEIPLANVTENFNMWKNDMVDQMHEDVISLWDQSLKPCVQLTPLCVTLNCSNVTYNVTYNNTNTNSSNNSSIAYNVTIDEERRNCSFNVTTEIRDKKKEVYALFYKLDLVPFGNSNSNNSSQYILINCNTSTIAQACPKISFDPIPIHYCAPAGYAILKCNNKTFNGTGPCNNVSTVQCTHGIKPVVSTQLLLNGSIAEGEIIIRSENLTNNVKTIIVHLNESVKIECMRPGNNTRKSIRIGPGQTFYATGAIIGDIRQAHCNISKNDWDKTLQRVGKKLTEYFPNKTIVFRPHSGGDPEITTHSFNCRGEFFYCNTTGLFNSTYMSNSTESNSSSNSSSNSTIILPCRIKQFVNMWQKVGRAIYAPPIAGNITCTSNITGLLLVRDGGTNNDTNDTEIFRPGGGNMRDNWRSELYKYKVVEIKPLGIAPTESKRRVVEREKR | ||||||
Domain | 539-729 | Retroviral envelope protein GP41-like | ||||
Sequence: MGAASITLTVQARQLLSGIVQQQSNLLRAIEAQQHMLQLTVWGIKQLQTRVLAIERYLKDQQLLGIWGCSGKLICTTAVPWNSSWSNRTYADIWDNLTWMQWDREINNYTGIIYKLLEDSQIQQEQNEKDLLALSNWQNLWSWFDISNWLWYIRIFVMIVGGLIGLRIIFAVLSIVNRVRQGYSPLSFQTL |
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusFragment
- Length865
- Mass (Da)97,689
- Last updated2013-11-13 v1
- Checksum1BE043CC9FE22CAE
Features
Showing features for non-terminal residue.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Non-terminal residue | 1 | |||||
Sequence: M |