T1SB41 · T1SB41_9GOBI

Function

function

Photoreceptor required for image-forming vision at low light intensity. While most salt water fish species use retinal as chromophore, most freshwater fish use 3-dehydroretinal, or a mixture of retinal and 3-dehydroretinal. Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change that activates signaling via G-proteins. Subsequent receptor phosphorylation mediates displacement of the bound G-protein alpha subunit by arrestin and terminates signaling.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Features

Showing features for site, binding site.

124520406080100120140160180200220240
Type
IDPosition(s)Description
Site69Plays an important role in the conformation switch to the active conformation
Binding site157Zn2+ (UniProtKB | ChEBI)
Binding site235Zn2+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentmembrane
Cellular Componentphotoreceptor outer segment
Molecular FunctionG protein-coupled photoreceptor activity
Molecular Functionmetal ion binding
Biological Processcellular response to light stimulus
Biological Processphototransduction
Biological Processvisual perception

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Rhodopsin

Gene names

    • Name
      Rhod1

Organism names

  • Taxonomic identifier
  • Organism
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Neoteleostei > Acanthomorphata > Gobiaria > Gobiiformes > Gobioidei > Gobiidae > Sicydiinae > Stiphodon

Accessions

  • Primary accession
    T1SB41

Subcellular Location

Membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane31-51Helical
Transmembrane71-89Helical
Transmembrane109-129Helical
Transmembrane159-179Helical
Transmembrane210-232Helical

Keywords

PTM/Processing

Features

Showing features for disulfide bond.

TypeIDPosition(s)Description
Disulfide bond66↔143

Keywords

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain10-245G-protein coupled receptors family 1 profile

Sequence similarities

Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.

Keywords

Family and domain databases

Protein family/group databases

Sequence

  • Sequence status
    Fragment
  • Length
    245
  • Mass (Da)
    27,709
  • Last updated
    2013-11-13 v1
  • Checksum
    0A6BDCAD7ED808DD
FFLILAGFPINFLTLYVTIEHKKLRTPLNYILLNLAVADLFMVFGGFTTTMYTSMHGYFVLGRLGCNLEGFFATLGGEIGLWSLVVLAIERWIVVCKPISNFRFGENHAIMGVALTWIMACSCAVPPLVGWSRYIPEGMQCSCGVDYYTRAEGFNNESFVIYMFIVHFSIPFTVIFFCYGRLLCAVKEAAAAQQESETTQRAEREVTRMVVIMVIAFLVSWLPYASVAWYIFTHQGSEFGPLFMT

Features

Showing features for non-terminal residue.

TypeIDPosition(s)Description
Non-terminal residue1
Non-terminal residue245

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
KF235574
EMBL· GenBank· DDBJ
AGR53674.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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