T0MJC2 · T0MJC2_CAMFR

Function

Catalytic activity

  • 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine + H2O = 1-hexadecanoyl-sn-glycero-3-phosphocholine + H+ + hexadecanoate
    This reaction proceeds in the forward direction.
  • 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphoethanolamine + H2O = (9Z,12Z)-octadecadienoate + 1-hexadecanoyl-sn-glycero-3-phosphoethanolamine + H+
    This reaction proceeds in the forward direction.
  • 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol) + H2O = (9Z)-octadecenoate + 1-hexadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) + H+
    This reaction proceeds in the forward direction.
  • 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H2O = (9Z)-octadecenoate + 1-hexadecanoyl-sn-glycero-3-phosphocholine + H+
    This reaction proceeds in the forward direction.
  • H2O + N-hexadecanoyl-1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine = (9Z)-octadecenoate + H+ + N-hexadecanoyl-1-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine
    This reaction proceeds in the forward direction.
  • a 1,2-diacyl-sn-glycero-3-phosphocholine + H2O = a 1-acyl-sn-glycero-3-phosphocholine + a fatty acid + H+
    EC:3.1.1.4 (UniProtKB | ENZYME | Rhea)

Cofactor

Ca2+ (UniProtKB | Rhea| CHEBI:29108 )

Note: Binds 1 Ca2+ ion per subunit.

Features

Showing features for binding site, active site.

TypeIDPosition(s)Description
Binding site20Ca2+ (UniProtKB | ChEBI)
Binding site22Ca2+ (UniProtKB | ChEBI)
Binding site24Ca2+ (UniProtKB | ChEBI)
Active site40
Binding site41Ca2+ (UniProtKB | ChEBI)
Active site84

GO annotations

AspectTerm
Cellular Componentextracellular region
Molecular Functioncalcium ion binding
Molecular Functioncalcium-dependent phospholipase A2 activity
Molecular Functionphospholipid binding
Biological Processarachidonic acid secretion
Biological Processlipid catabolic process
Biological Processnegative regulation of T cell proliferation
Biological Processphospholipid metabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Phospholipase A2
  • EC number

Gene names

    • ORF names
      CB1_001086048

Organism names

Accessions

  • Primary accession
    T0MJC2

Proteomes

Subcellular Location

Keywords

  • Cellular component

PTM/Processing

Features

Showing features for disulfide bond.

TypeIDPosition(s)Description
Disulfide bond21↔37
Disulfide bond36↔90
Disulfide bond43↔83
Disulfide bond70↔81

Keywords

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain1-111Phospholipase A2

Sequence similarities

Belongs to the phospholipase A2 family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    111
  • Mass (Da)
    12,934
  • Last updated
    2013-10-16 v1
  • Checksum
    5E88F7258E698658
MIEDVTGKPALESFGFYGCYCGWGGKGTPVDAIDWCCWWHDVCYAELERKGYNVLTQSYRYRVRQGLVTCELGSHCQMELCACDQKLVHCLKRNRRSYSSLYQYFPNFLCI

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
KB017313
EMBL· GenBank· DDBJ
EQB78640.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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