T0KUH0 · T0KUH0_COLGC

Function

function

Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

FAD (UniProtKB | Rhea| CHEBI:57692 )

Pathway

Carbohydrate metabolism; tricarboxylic acid cycle; fumarate from succinate (eukaryal route): step 1/1.

Features

Showing features for binding site, active site.

TypeIDPosition(s)Description
Binding site64-69FAD (UniProtKB | ChEBI)
Binding site87-102FAD (UniProtKB | ChEBI)
Binding site271FAD (UniProtKB | ChEBI)
Binding site292substrate
Binding site304substrate
Active site336Proton acceptor
Binding site403substrate
Binding site437FAD (UniProtKB | ChEBI)
Binding site448substrate
Binding site453-454FAD (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentmitochondrial inner membrane
Molecular Functionelectron transfer activity
Molecular Functionflavin adenine dinucleotide binding
Molecular Functionsuccinate dehydrogenase (quinone) activity
Biological Processmitochondrial electron transport, succinate to ubiquinone
Biological Processtricarboxylic acid cycle

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial
  • EC number

Gene names

    • ORF names
      CGLO_00469

Organism names

Accessions

  • Primary accession
    T0KUH0

Proteomes

Subcellular Location

Membrane
; Peripheral membrane protein
Mitochondrion inner membrane
; Peripheral membrane protein

Keywords

  • Cellular component

PTM/Processing

Features

Showing features for modified residue.

TypeIDPosition(s)Description
Modified residue95Tele-8alpha-FAD histidine

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain59-454FAD-dependent oxidoreductase 2 FAD binding
Domain510-644Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal

Sequence similarities

Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    644
  • Mass (Da)
    70,574
  • Last updated
    2013-10-16 v1
  • Checksum
    CE7D4778A0B7D56B
MASSMALRRFAAARPAFSQARAFSTTRSAARVFANQPLRAKEASPYVSNKYPVIDHEYDAIVVGAGGAGLRAAFGLAEAGFNTACISKLFPTRSHTVAAQGGINAALGNMHEDDWRWHMYDTVKGSDWLGDQDAIHYMTREAPASIVELENYGCPFSRTEDGKIYQRAFGGQSQKFGKGGQAYRCCAAEDRTGHALLHTLYGQSLRHNTNYFIEYFALDLIMQDGECRGVLAYNQEDGTLHRFLANHTVLATGGYGRAYFSCTSAHTCTGDGMAMVARAGLPNQDLEFVQFHPTGIYGAGCLITEGARGEGGYLLNSEGERFMERYAPTAKDLASRDVVSRSMTMEIRDGRGVGEDKDHIFLQLSHLPAEVLHERLPGISETAGIFAGVDVRTQPIPVLPTVHYNMGGIPTKYTGEVITVDENGKDKVVPGLFACGEAACVSVHGANRLGANSLLDLVVFGRAVSHTIRDKFSPGTKHKPLAADAGAEHIEVLDKVRTSEGPRTTADVRLSMQKAMQTEVSVFRTQESLDEGVRKMVEIDAQFPEVGIKDRSMIWNSDLVETLELRNLLTCAIQTATSAAARKESRGAHAREDFPERDDKEWMKHTLSFQKQPHGKVDLSYRGVIANTLDENECKAVPPFKRVY

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AMYD01000120
EMBL· GenBank· DDBJ
EQB59172.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

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